Mental health disorders
Low vitamin D levels linked to depression and cognitive deficits in psychotic disorders
Study shows a link between vitamin D and depression, while vitamin D deficiency was linked to impairments in processing speed and verbal fluency.
Previous research has shown that low vitamin D levels may be associated with increased disease severity in psychotic disorders.
To explore which symptoms are affected by vitamin D status, a team from the Norwegian Centre for Mental Disorders Research recruited 358 patients and compared their vitamin D levels against measures of symptom severity.
The researchers found that low vitamin D levels were significantly associated with negative symptoms and depression. When they studied the performance of 225 patients alongside 159 healthy controls in cognitive function tests, vitamin D deficiency was also linked to impairments in processing speed and verbal fluency.
The team, who reported their findings at the International Early Psychosis Association Meeting in Milan in October 2016, say the results show the need for large randomised trials to explore any potential benefit of vitamin D in psychotic disorders.
Citation: Clinical Pharmacist DOI: 10.1211/CP.2016.20201899
Recommended from Pharmaceutical Press