Cookie policy: This site uses cookies (small files stored on your computer) to simplify and improve your experience of this website. Cookies are small text files stored on the device you are using to access this website. For more information please take a look at our terms and conditions. Some parts of the site may not work properly if you choose not to accept cookies.

Join

Subscribe or Register

Existing user? Login

Paediatrics

No evidence for hydrolysed infant formula in allergy prevention

Researchers find no protective effect of hydrolysed formula against allergic and autoimmune disease, conflicting with international guidelines.

Young baby drinking from bottle

Source: Shutterstock

International guidelines currently recommend the use of hydrolysed formula over standard formula in the first four to six months of life

International guidelines recommend that infants who aren’t breastfed in the first four to six months of life are fed hydrolysed formula milk, in which the proteins are broken down, to help prevent allergic and autoimmune diseases, such as eczema and wheeze. 

To inform UK guidelines, the Food Standards Agency commissioned a systematic review of the literature. Researchers analysed data from 37 trials and found that, compared with standard cows’ milk formula, there was “no consistent evidence” to support a protective effect of hydrolysed formula against allergic and autoimmune disease up to the age of 14 years. Furthermore, some studies had a high risk of bias, evidence of conflict of interest and inadequate randomisation. 

In The BMJ (online, 8 March 2016)[1] the authors conclude that the findings do not support the current recommendations and suggest that future studies should be independently funded.

Citation: The Pharmaceutical Journal DOI: 10.1211/CP.2016.20200859

Have your say

For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.

Recommended from Pharmaceutical Press

  • Sport and Exercise Medicine for Pharmacists

    Sport and Exercise Medicine for Pharmacists

    All the information you need to provide patients with evidence-based advice on sports and exercise related health matters.

    £27.00Buy now
  • Introduction to Renal Therapeutics

    Introduction to Renal Therapeutics

    Introduction to Renal Therapeutics covers all aspects of drug use in renal failure. Shows the role of the pharmacist in patient care for chronic kidney disease.

    £38.00Buy now
  • Pathology and Therapeutics for Pharmacists

    Pathology and Therapeutics for Pharmacists

    An practical, integrated approach to the pathophysiological and pharmacotherapeutic principles underlying the treatment of disease.

    £54.00Buy now
  • Drugs and the Liver

    Drugs and the Liver

    Drugs and the Liver assists practitioners in making pragmatic choices for their patients. It enables you to assess liver function and covers the principles of drug use in liver disease.

    £38.00Buy now
  • Popular Medicines

    Popular Medicines

    An illustrated history of some of the most popular branded medicines. Includes colourful historical adverts and details of the medicine's formula and intended purpose.

    £22.00Buy now

Search an extensive range of the world’s most trusted resources

Powered by MedicinesComplete
  • Print
  • Share
  • Comment
  • Save
  • Print Friendly Version of this pagePrint Get a PDF version of this webpagePDF

Supplementary images

  • Young baby drinking from bottle

Newsletter Sign-up

Want to keep up with the latest news, comment and CPD articles in pharmacy and science? Subscribe to our free alerts.