Cookie policy: This site uses cookies (small files stored on your computer) to simplify and improve your experience of this website. Cookies are small text files stored on the device you are using to access this website. For more information please take a look at our terms and conditions. Some parts of the site may not work properly if you choose not to accept cookies.

Join

Subscribe or Register

Existing user? Login

Chemoprevention

Risk modelling study suggests aspirin’s harms outweigh benefits for younger women

Aspirin (molecular structure pictured) can reduce cancer incidence and mortality. However, it does not outweigh the risks of major gastrointestinal bleeding in women, researchers find

Source: Wikimedia Commons

For most women, the long-term benefits of aspirin did not outweigh the increase in major gastrointestinal bleeding

Emerging data show that daily aspirin reduces cancer incidence and mortality. However, the role of aspirin in primary prevention remains unclear in view of the associated increase in major bleeding.

In an attempt to answer this question, Frank Visseren, from University Medical Centre Utrecht, the Netherlands, and team used data from the Women’s Health Study to model the effect of 15 years’ treatment with alternate-day low-dose aspirin on the combination of cardiovascular disease, cancer and major bleeding events in initially healthy women.

For most women, the long-term benefits of aspirin did not outweigh the increase in major gastrointestinal bleeding. However, selective treatment of women aged 65 years and over “may improve net benefit”, conclude the authors in Heart (online, 4 December 2014)[1].

Citation: The Pharmaceutical Journal DOI: 10.1211/PJ.2014.20067431

Have your say

For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.

Recommended from Pharmaceutical Press

  • Print
  • Share
  • Comment
  • Save
  • Print Friendly Version of this pagePrint Get a PDF version of this webpagePDF

Newsletter Sign-up

Want to keep up with the latest news, comment and CPD articles in pharmacy and science? Subscribe to our free alerts.