Cookie policy: This site uses cookies (small files stored on your computer) to simplify and improve your experience of this website. Cookies are small text files stored on the device you are using to access this website. For more information please take a look at our terms and conditions. Some parts of the site may not work properly if you choose not to accept cookies.

Join

Subscribe or Register

Existing user? Login

Diabetes

Statins may be linked with type 2 diabetes risk in prospective study

Researchers found that ever use of statins was associated with a 38% higher risk of incident type 2 diabetes compared with never use.

Use of statins may be associated with an increased risk of developing type 2 diabetes, results from a prospective study show (5 March 2019)[1].

Researchers analysed data on 9,535 people without diabetes at baseline who were followed up from 1997 to 2012.

During a median follow-up of four years, it was found that ever use of statins was associated with a 38% higher risk of incident type 2 diabetes compared with never use. When stratified by body mass index (BMI), this relationship was only significant in overweight and obese people (hazard ratio: 1.42) and not in those with a normal BMI.

Baseline statin users also had higher concentrations of serum fasting insulin and insulin resistance compared with non-users.

The researchers explained that several observational studies had identified an elevated risk of incident type 2 diabetes in statin users. They said the findings underlined the importance of managing lifestyle factors when treating patients with statins.

Writing in the British Journal of Clinical Pharmacology, the researchers said: “It is necessary to take statin diabetogenicity into consideration in clinical practice when statin is indicated, emphasising the concomitant need for dietary measures and exercise.”

  • This article was amended on 1 May 2019 to clarify that statin use may be associated with an increased risk of type 2 diabetes

Citation: Clinical Pharmacist DOI: 10.1211/CP.2019.20206385

Have your say

For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.

Recommended from Pharmaceutical Press

  • BNF and BNF for Children

    BNF and BNF for Children

    Now available as a 2 year print subscription to both the BNF and BNFC, ensuring you have the latest medicines information as it publishes and at a greatly reduced price.

    £262.50Buy now
  • Patient Care in Community Practice

    Patient Care in Community Practice

    Patient Care in Community Practice is a unique, practical guide for healthcare professionals or carers. Covers a range of non-medicinal products suitable for use at home.

    £22.00Buy now
  • Clinical Pharmacokinetics

    Clinical Pharmacokinetics

    A practical guide to the use of pharmacokinetic principles in clinical practice. Includes case studies with questions and answers.

    £33.00Buy now
  • Strategic Medicines Management

    Strategic Medicines Management

    A practical guide to influencing the availability of medicines, and policies of their use. Focuses on the strategic elements of medicines management.

    £33.00Buy now
  • Introduction to Renal Therapeutics

    Introduction to Renal Therapeutics

    Introduction to Renal Therapeutics covers all aspects of drug use in renal failure. Shows the role of the pharmacist in patient care for chronic kidney disease.

    £38.00Buy now

Search an extensive range of the world’s most trusted resources

Powered by MedicinesComplete
  • Print
  • Share
  • Comment
  • Save
  • Print Friendly Version of this pagePrint Get a PDF version of this webpagePDF

Newsletter Sign-up

Want to keep up with the latest news, comment and CPD articles in pharmacy and science? Subscribe to our free alerts.