Anti-inflammatory agents
Study results do not support use of hydroxychloroquine in hand osteoarthritis
A study published in the Annals of Internal Medicine has shown that using hydroxychloroquine has no significant effect on osteoarthritic pain.
There is anecdotal evidence that the slow-acting anti-inflammatory treatment hydroxychloroquine, used to treat rheumatoid arthritis, could also be effective in osteoarthritis. However, data on this are limited.
In the Annals of Internal Medicine (20 February 2018), researchers carried out a 12-month randomised trial involving 248 patients with hand osteoarthritis and moderate-to-severe pain who were assigned to 200–400mg hydroxychloroquine or placebo, in addition to ongoing usual care[1].
At six months, the team found that the average hand pain score over the prior two weeks was 5.66 out of 10 in the active treatment group, compared with 5.49 in the placebo group, a non-significant difference.
The results, therefore, do not provide evidence to support the use of hydroxychloroquine in hand osteoarthritis, the researchers concluded.
Citation: Clinical Pharmacist DOI: 10.1211/CP.2018.20204612
Recommended from Pharmaceutical Press
- Previous
- Next
Patient Care in Community Practice
Patient Care in Community Practice is a unique, practical guide for healthcare professionals or carers. Covers a range of non-medicinal products suitable for use at home.
£22.00Buy now
Clinical Pharmacokinetics
A practical guide to the use of pharmacokinetic principles in clinical practice. Includes case studies with questions and answers.
£33.00Buy now
Strategic Medicines Management
A practical guide to influencing the availability of medicines, and policies of their use. Focuses on the strategic elements of medicines management.
£33.00Buy now
Sport and Exercise Medicine for Pharmacists
All the information you need to provide patients with evidence-based advice on sports and exercise related health matters.
£27.00Buy now
Introduction to Renal Therapeutics
Introduction to Renal Therapeutics covers all aspects of drug use in renal failure. Shows the role of the pharmacist in patient care for chronic kidney disease.
£38.00Buy now
Print 
PDF
Have your say
For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.