Cookie policy: This site uses cookies (small files stored on your computer) to simplify and improve your experience of this website. Cookies are small text files stored on the device you are using to access this website. For more information please take a look at our terms and conditions. Some parts of the site may not work properly if you choose not to accept cookies.


Subscribe or Register

Existing user? Login

Sexually transmitted diseases

Two doses of HPV vaccine enough to protect against genital warts

US study shows that three doses of the Human Papillomavirus vaccine does not provide any more protection than two against genital warts.

Three-dose quadrivalent Human Papillomavirus (HPV) vaccination in reducing cervical, vulvar, vaginal and anal dysplasia has been demonstrated in clinical trials to be effective but data on fewer than three doses are limited.

US researchers selected insurance claim data from 387,906 adolescent females with a mean age of 14.73 years. Fifty-two per cent of the girls remained unvaccinated during the 5.64 year average follow-up time, 7.8% received one dose, 9.4% received two doses and 30.7% received three doses.

The overall rate of genital warts was 1.97/1000 person years and the rate decreased with each additional HPV vaccine dose. Receipt of three doses was significantly more effective than one dose or no doses but the difference between two and three doses was not significant.

Publishing in Sexually Transmitted Diseases[1] (online, 15 May 2017), the researchers conclude that at least two doses of HPV vaccine are necessary to protect against genital warts but further studies are required to assess cervical dysplasia or cancer outcomes.

Citation: Clinical Pharmacist DOI: 10.1211/CP.2017.20202867

Have your say

For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.

Recommended from Pharmaceutical Press

Search an extensive range of the world’s most trusted resources

Powered by MedicinesComplete
  • Print
  • Share
  • Comment
  • Save
  • Print Friendly Version of this pagePrint Get a PDF version of this webpagePDF

Supplementary images

  • Young girl receives HPV vaccine

Newsletter Sign-up

Want to keep up with the latest news, comment and CPD articles in pharmacy and science? Subscribe to our free alerts.