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Doctor measuring a patient's blood pressure

Triple combination antihypertensive pill effective for blood pressure controlSubscription

A fixed-dose triple combination antihypertensive pill was more effective at controlling blood pressure than usual care, the results of a randomised trial in Sri Lanka show

3D model of influenza A virions

Obesity may increase influenza A virus transmission riskSubscription

Obese adults shed influenza A virus for almost 50% longer than non-obese adults, research published in the Journal of Infectious Diseases shows.

Transdermal pain relief

Transdermal buprenorphine poorly tolerated in people with dementiaSubscription

A study of transdermal analgesics in people living with dementia has shown that more than half discontinue buprenorphine owing to adverse events.

People exercising

More exercise not always better for mental health, study findsSubscription

Researchers from the United States have found that exercise is associated with a reduced mental health burden, but this benefit does not always continue to increase with duration and frequency.

Lung function testing

Asthma care in England needs to be more proactive, researchers saySubscription

An audit of data from Bedfordshire Clinical Commissioning Group in England has found inconsistencies in asthma care that could leave high-risk patients unidentified and at risk of death.

Healthy foods

Healthy diet linked to improved asthma symptomsSubscription

Research across a large cohort using three different quality measures has shown that a healthy diet is associated with a reduced likelihood of experiencing asthma symptoms

Blood glucose testing

Continuing metformin when introducing sulfonylureas is safer than switching in T2DM, research showsSubscription

Switching to sulfonylureas increases the risk of serious adverse events compared with remaining on metformin in people with type 2 diabetes mellitus, according to research published in The BMJ.

Doctor writing a note

GP-based audit intervention helps cut high-risk prescribingSubscription

Results from a pharmacist-delivered audit pilot show that it reduced levels of high-risk prescribing in general practice, study results have shown.

Omega 3 tablets

Omega-3 supplements do not protect against cardiovascular disease, meta-analysis showsSubscription

A meta-analysis of 79 trials showed that increasing long-chain omega-3 had little or no effect on death from all causes, cardiovascular deaths, cardiovascular events, coronary heart disease deaths, stroke or arrhythmia.

Degludec insulin molecule

Insulin degludec significantly improves blood sugar control compared with insulin glargine, data show Subscription

Using electronic health record data, researchers found that HbA1c levels declined by 1.5% among insulin degludec-treated patients compared with 1.2% in those treated with insulin glargine U300 over six months.

Woman with diabetes injecting insulin

Glucose-lowering therapy does not slow progression in young people with type 2 diabetesSubscription

Treatment with glucose-lowering therapy does not maintain or improve pancreatic beta-cell function in young people recently diagnosed with impaired glucose tolerance or type 2 diabetes mellitus, a study has shown.

Apixaban molecular structure

Direct oral anticoagulants carry lower risk of major bleeding versus warfarin, data showSubscription

Research from primary care suggests apixaban may be the safest of the direct oral anticoagulants overall.

Woman sitting, lower back pain

Gabapentinoids ineffective for lower back pain, review findsSubscription

A review published in the Canadian Medical Association Journal has backed up guidance stating that anticonvulsants are ineffective for treating lower back pain.

Old man walking with cane

Impulse-control disorders common in Parkinson’s patients taking dopamine agonistsSubscription

Researchers find that after five years of follow-up, more than half of people taking dopamine agonists for management of Parkinson’s disease developed impulse-control disorders.


Access to personalised cardiovascular risk information boosts lifestyle changeSubscription

Research has shown that giving patients personalised information about their disease risk can motivate them to make lifestyle changes.

Scanning electron micrograph of a prostate cancer cell

Pembrolizumab effective in some men with advanced prostate cancerSubscription

A study of 258 men with otherwise untreatable prostate cancer shows that the rate of disease control or response lasting six months or more was 11%, with two patients showing complete response.

Atrial fibrillation monitor

Sleep disruption linked to atrial fibrillation riskSubscription

Sleep disruption is an important risk factor for developing atrial fibrillation, study results show.

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