Aspirin reduces the risk of all-cause death or hospitalisation for heart failure in patients with concomitant type 2 diabetes and heart failure but increases the risk of non-fatal heart attack or stroke.
Research has shown ‘marked improvements’ in PTSD symptoms after MDMA use during psychotherapy.
Research into long-term proton pump inhibitor use among older adults has led to cautions over pneumonia risk.
Use of a body-worn sensor to track movements could help grade a person’s severity of multiple sclerosis, guiding treatment, research has shown.
7-day antibiotic course ‘non-inferior’ to 14 days for treatment of Gram-negative bacteraemiaSubscription
Research has shown that shorter antibiotic courses are not inferior to longer courses for the treatment of Gram-negative bacteraemia.
An electronic medical record alert system could potentially reduce coprescribing and related overdose deaths, researchers have found.
Interventions to reduce blood pressure may help to improve reproductive outcomes in healthy young women, research has found.
Introducing first-line immunotherapy could benefit long-term outcomes in advanced non-small-cell lung cancer (NSCLC), a study has revealed.
Dipeptidyl peptidase-4 (DPP-4) inhibitors do not lower death rates in patients with type 2 diabetes, an analysis comparing them with other common treatments has shown.
Use of non-steroidal anti-inflammatory drugs (NSAIDs), with or without paracetamol, can provide a better balance of benefits and risks compared with opioids for the treatment of acute dental pain, a review has revealed.
There is no evidence for the benefit of omega-3 acid supplementation in treating symptoms of dry eye disease, a study has shown.
Increase in potentially inappropriate medicines use seen in all older adults, study results suggestSubscription
After assessing patterns of medicines use in patients with and without dementia, researchers found that the risk of potentially inappropriate medicines use significantly increased in all groups
Results from an ongoing trial of 228 patients with acute major bleeding show that patients taking andexanet experienced a reduction in anti-FXa activity.
Researchers have identified 14 new independent risk variants associated with depression following a genome-wide association study of 322,580 people.
It is well known that older adults with cardiovascular risk factors are more likely to experience depression than others. However, research has shown that dietary modification could help lower depression risk in this group.
The pro-inflammatory cytokine interleukin-1 plays a significant role in brain injury following ischemic stroke by inducing peripheral inflammatory mediators, such as interleukin-6. However, pre-clinical studies show its effects are reduced by the interleukin-1 receptor antagonist.
No significant difference between LAMAs and LABAs in treating persistent asthma, research findsSubscription
Data from 15 randomised trials show that while long-acting muscarinic antagonists reduced exacerbation risk by a third, there was no significant improvement compared with long-acting beta-agonists.
ACE inhibitors and beta-blockers reduce risk of cardiotoxicity for some Herceptin patientsSubscription
Researchers conclude that prophylactic use of lisinopril or carvedilol should be considered in patients who could benefit from anthracycline treatment prior to trastuzumab (Herceptin).
Using data from more than 1.5 million patients who underwent joint replacement surgery, researchers found a stepwise increase in beneficial effects as the number of analgesic modes increased.