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Aspirin blister packs

Aspirin lowers risk of death in people with concomitant heart failure and diabetesSubscription

Aspirin reduces the risk of all-cause death or hospitalisation for heart failure in patients with concomitant type 2 diabetes and heart failure but increases the risk of non-fatal heart attack or stroke.

Ecstasy pills

MDMA could enhance psychotherapy outcomes in people with PTSDSubscription

Research has shown ‘marked improvements’ in PTSD symptoms after MDMA use during psychotherapy.

X-ray of a patient's lungs with pneumonia

Proton pump inhibitors linked to pneumonia risk beyond first year of useSubscription

Research into long-term proton pump inhibitor use among older adults has led to cautions over pneumonia risk.

MRI scan

'Real-life' gait analysis can guide MS treatment, researchers saySubscription

Use of a body-worn sensor to track movements could help grade a person’s severity of multiple sclerosis, guiding treatment, research has shown.

Acinetobacter SEM, gram-negative bacteria

7-day antibiotic course ‘non-inferior’ to 14 days for treatment of Gram-negative bacteraemiaSubscription

Research has shown that shorter antibiotic courses are not inferior to longer courses for the treatment of Gram-negative bacteraemia.

Benzodiazepine, anxiolytic pills

Prescribing alerts could cut opioid and benzodiazepine coprescribingSubscription

An electronic medical record alert system could potentially reduce coprescribing and related overdose deaths, researchers have found.

Woman taking blood pressure with doctor

Preconception blood pressure linked to pregnancy loss riskSubscription

Interventions to reduce blood pressure may help to improve reproductive outcomes in healthy young women, research has found.

3D CT scan showing lung cancer

Addition of pembrolizumab to chemotherapy extends survival in advanced lung cancerSubscription

Introducing first-line immunotherapy could benefit long-term outcomes in advanced non-small-cell lung cancer (NSCLC), a study has revealed.

Senior woman taking pin-prick blood test

DPP-4 inhibitors have no mortality benefit in type 2 diabetes, analysis showsSubscription

Dipeptidyl peptidase-4 (DPP-4) inhibitors do not lower death rates in patients with type 2 diabetes, an analysis comparing them with other common treatments has shown.

Teeth x-ray, dental pain concept

NSAIDs preferred choice for acute dental pain, review findsSubscription

Use of non-steroidal anti-inflammatory drugs (NSAIDs), with or without paracetamol, can provide a better balance of benefits and risks compared with opioids for the treatment of acute dental pain, a review has revealed.

Red irritated eye

Omega-3 supplements do not improve dry eye symptoms, study findsSubscription

There is no evidence for the benefit of omega-3 acid supplementation in treating symptoms of dry eye disease, a study has shown.

Close up of a full pill box

Increase in potentially inappropriate medicines use seen in all older adults, study results suggestSubscription

After assessing patterns of medicines use in patients with and without dementia, researchers found that the risk of potentially inappropriate medicines use significantly increased in all groups

Human blood clotting light micrograph

Andexanet shows promise in patients taking new anticoagulants Subscription

Results from an ongoing trial of 228 patients with acute major bleeding show that patients taking andexanet experienced a reduction in anti-FXa activity.

Man clutching head in dark tunnel, depression concept

Study identifies genes potentially linked to depression Subscription

Researchers have identified 14 new independent risk variants associated with depression following a genome-wide association study of 322,580 people.

Healthy food, fruit and vegetables

Antihypertension diet also lowers depression risk in older adultsSubscription

It is well known that older adults with cardiovascular risk factors are more likely to experience depression than others. However, research has shown that dietary modification could help lower depression risk in this group.

3D CT scan of a person with a stroke

Rheumatoid arthritis drug may reduce inflammation after strokeSubscription

The pro-inflammatory cytokine interleukin-1 plays a significant role in brain injury following ischemic stroke by inducing peripheral inflammatory mediators, such as interleukin-6. However, pre-clinical studies show its effects are reduced by the interleukin-1 receptor antagonist.

Asthma inhaler, salmeterol, long acting beta agonists (LABA)

No significant difference between LAMAs and LABAs in treating persistent asthma, research findsSubscription

Data from 15 randomised trials show that while long-acting muscarinic antagonists reduced exacerbation risk by a third, there was no significant improvement compared with long-acting beta-agonists.

Lisinopril ACE inhibitor, molecular structure

ACE inhibitors and beta-blockers reduce risk of cardiotoxicity for some Herceptin patientsSubscription

Researchers conclude that prophylactic use of lisinopril or carvedilol should be considered in patients who could benefit from anthracycline treatment prior to trastuzumab (Herceptin).

Coloured x-ray of a hip replacement

Large study supports use of multimodal pain management after joint replacementSubscription

Using data from more than 1.5 million patients who underwent joint replacement surgery, researchers found a stepwise increase in beneficial effects as the number of analgesic modes increased.

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