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Antibiotic resistance: a fragile defence

Last defence dam in antimicrobial resistance

Around 25,000 people die in the European Union each year from infections resistant to antibiotics. Third-generation cephalosporins are often useless against common bacteria like Escherichia coli, and fluoroquinolones are no longer the treatment of choice for gonorrhoea because resistance has become widespread. Here, you can find news stories and articles about the issue.

Carbapenem resistant bacteria acinetobacter spp

Cefiderocol effective for carbapenem-resistant Gram-negative infectionsSubscription

The clinical and microbiological outcomes of cefiderocol, a new antibiotic, were similar to the best available therapy for patients with life-threatening carbapenem-resistant infections, a phase III study has suggested.

honey

Honey effective at relieving URTI symptoms, analysis concludesSubscription

Honey is superior to usual care for improving symptoms of upper respiratory tract infection symptoms, researchers have concluded.

researcher in laboratory

Point-of-care testing for influenza could improve antimicrobial use, feasibility study concludesSubscription

Point-of-care testing for influenza is feasible in primary care and may improve antimicrobial use, a study in the British Journal of General Practice has concluded.

Amoxicillin capsules

Doubling of penicillin allergy reports may put a million hospital patients at greater risk each yearSubscription

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An analysis of hospital admissions data by The Pharmaceutical Journal shows that between 2012/2013 and 2018/2019, the number of hospital admissions in England where the patient had a diagnostic ‘label’ of penicillin allergy almost doubled, from 575,000 to 1.1 million.

More on antimicrobial resistance

Stuck in the 1950s: why UTI diagnosis badly needs an update

Stuck in the 1950s: why UTI diagnosis badly needs an updateSubscription

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Urinary tract infections are the second most common reason for prescribing an antibiotic and, with antimicrobial stewardship a priority for the government, the stakes for accurate diagnosis are being raised ever higher.

INFOGRAPHIC Macrolide full

Preserving macrolidesSubscription

By , Priya N Chudasama

Macrolide antibiotics have many uses, particularly for penicillin-allergic patients, but recent trends suggest that resistance is increasing among Gram-positive infections.

Dangerous label false penicillin allergies fuel antibiotic resistance

Dangerous labels: incorrect penicillin allergies fuel antibiotic resistanceSubscription

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The vast majority of people with a penicillin allergy label are, in fact, not allergic, leading to significant healthcare implications. Experts say it is now time for a national “de-labelling” drive to help conserve vital antibiotics.

'As I listen, I form an action plan' — a day in the life of a patient support officer

'As I listen, I form an action plan' — a day in the life of a patient support officer Subscription

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When her son fell chronically ill, Arlene Brailey found the motivation to take on a role dedicated to helping patients with resistant bacterial infections find support and trustworthy information.

More on antimicrobial resistance

INFOGRAPHIC Macrolide full

Preserving macrolidesSubscription

By , Priya N Chudasama

Macrolide antibiotics have many uses, particularly for penicillin-allergic patients, but recent trends suggest that resistance is increasing among Gram-positive infections.

antimicrobial resistance

Evidence shows the antibiotics market is failing, but here is how it can be revivedSubscription

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A core group of pharmaceutical companies are making progress in tackling the spread of antimicrobial resistance, but change is not happening at the scale needed to radically impact the threat from drug resistance.

Pharmacists should make themselves familiar with the Antifungal Drug Interactions DatabaseSubscription

In this time of growing antimicrobial resistance, we do not have unlimited ways to effectively treat a systemic infection. We must be antimicrobial stewards and use antimicrobials responsibly to preserve their effectiveness[1]. This applies to antifungals too — not just antibiotics

We need a national de labelling drive for patients with penicillin allergy

We need a national de-labelling drive for patients with penicillin allergySubscription

False penicillin allergies are placing patients at risk of resistant infections and are a threat to antimicrobial stewardship; we must safely de-label patients to avoid these costs to public health.

More on antimicrobial resistance

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