Cookie policy: This site uses cookies (small files stored on your computer) to simplify and improve your experience of this website. Cookies are small text files stored on the device you are using to access this website. For more information please take a look at our terms and conditions. Some parts of the site may not work properly if you choose not to accept cookies.

Stem cell therapy

Human embryonic stem cells appear to be safe for use in macular degeneration

Human embryonic stem cells show evidence of medium to long-term safety and graft survival when transplanted into patients, study finds

Source: Nissim Benvenisty, Russo E / Wikimedia Commons

Human embryonic stem cells show evidence of medium to long-term safety when transplanted into patients, study finds

Human embryonic stem cells (hESCs) hold promise as a source of therapeutic cells for a wide range of degenerative diseases, but their plasticity and capacity for self-renewal has prompted safety concerns.

A study published in The Lancet (online, 15 October 2014)[1] provides the first evidence of medium- to long-term safety, graft survival and possible biological activity of hESC-derived cells transplanted into patients.

Robert Lanza, from Advanced Cell Technology in Marlborough, Massachusetts, and team transplanted hESC-derived retinal pigment epithelium in 18 patients with macular degeneration. The cells appeared safe and were well tolerated up to 37 months after transplantation. Furthermore, visual acuity improved in 10 of 18 treated eyes and improved or remained the same in 7 eyes, whereas untreated control eyes showed no such improvement.

Citation: The Pharmaceutical Journal DOI: 10.1211/PJ.2014.20066859

Have your say

For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.

Recommended from Pharmaceutical Press

  • Patient Care in Community Practice

    Patient Care in Community Practice

    Patient Care in Community Practice is a unique, practical guide for healthcare professionals or carers. Covers a range of non-medicinal products suitable for use at home.

    £22.00Buy now
  • Pharmacy OSCEs

    Pharmacy OSCEs

    The only pharmacy-specific OSCE revision guide. This easy-to-use book covers the key competencies that will be tested in your exams.

    £25.00Buy now
  • Drugs and the Liver

    Drugs and the Liver

    Drugs and the Liver assists practitioners in making pragmatic choices for their patients. It enables you to assess liver function and covers the principles of drug use in liver disease.

    £38.00Buy now
  • Physicochemical Principles of Pharmacy

    Physicochemical Principles of Pharmacy

    This established textbook covers every aspect of drug properties from the design of dosage forms to their delivery by all routes to sites of action in the body.

    £48.00Buy now
  • Introduction to Renal Therapeutics

    Introduction to Renal Therapeutics

    Introduction to Renal Therapeutics covers all aspects of drug use in renal failure. Shows the role of the pharmacist in patient care for chronic kidney disease.

    £38.00Buy now

Search an extensive range of the world’s most trusted resources

Powered by MedicinesComplete
  • Print
  • Share
  • Comment
  • Save
  • Print Friendly Version of this pagePrint Get a PDF version of this webpagePDF
grouped logos

Site powered by Webvision