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Nexium Control: For 24hr relief and protection from heartburn

The only GSL heartburn medication to provide all day and night relief* with just one pill a day. 

Many heartburn sufferers rely on antacids and alginates, however these treatments do not deliver the sustained relief that frequent sufferers require[1].

Nexium Control is a proton pump inhibitor (PPI) containing 20mg esomeprazole. It works by reducing the production of acid in the stomach, providing 24-hour protection from heartburn. 

Nexium control pillbox

5 reasons to recommend Nexium Control®

  • 24 hour relief and protection from frequent heartburn[2]
  • NICE guidelines recommend PPIs as first line prescription treatment for frequent heartburn[3]
  • Treats the cause and symptoms of frequent heartburn by reducing the production of stomach acid. Just one tablet a day provides 24hr protection
  • As the #1 acid blocker brand worldwide, it has been used by millions of patients[4]
  • A short term treatment which gives the oesophagus some time to heal

Product of the year 2016 logo


Positive consumer experience

  • Voted as the 2016 General Healthcare ‘Product of the Year’
  • 8 out of 10 consumers experienced a meaningful improvement in heartburn symptoms after using Nexium Control[2]
  • Up to 4 out of 5 nights were heartburn-free when taking Nexium Control for 14 days[2]

Duration of heartburn medications

Duration of heartburn medications, from antacids, alginates, H2 Blockers to PPIs

Antacids: Lasts up to 2 hrs. Neutralises acid. Quick, short term relief of symptoms of occasional heartburn
Alginates: Lasts up to 4 hrs. Forms a raft on top of stomach contents. Quick, short term relief of symptoms of occasional heartburn
H2 Blockers (i.e. Ranitidine): Lasts up to 12 hrs. Blocks one of the three signals that stimulate acid production. Intermediate duration relief of heartburn
PPIs (i.e. esomeprazole): Lasts up to 24 hrs. Acts on proton pumps to reduce acid production. 24hr relief and protection from frequent heartburn which occurs twice per week or more

24 hr heartburn protection for less than £1 a day

Cost comparison table based on frequent heartburn sufferers needing multiple daily doses to achieve longer term relief.

Product name Pack size Max daily dose MRRP [5]Daily cost 
Nexium Control7’s £6.99£1.00 
Nexium Control 14’s £11.99 £0.86 
Gaviscon peppermint tablets 32’s 16 £4.29 £2.14 
Gaviscon Double Action Liquid 300ml 80ml £7.89 £2.10 
Rennie peppermint tablets 24’s 10 £2.15 £0.90 
Zantac 75 tablets 12’s £4.19 £0.70 


Free 30-minute CPD training: OTC management of acid reflux – communicating with your patient 

Complete online at

For further information about Nexium Control® please visit

*As on UK market data Aug 16

**Winner General Healthcare Category.  Survey of 11,586 people by TNS.  Date of preparation: March 2016

Name of product: Nexium Control 20 mg gastro resistant tablets. Active ingredient: Esomeprazole. Supply classification: General Sales List (GSL). Indications: The short term treatment of reflux symptoms (e.g. heartburn and acid regurgitation) in adults. Further information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: or from Pfizer Consumer Healthcare Ltd, Walton Oaks, Surrey, KT20 7NS. Cost: Pack of 7 tablets Excl VAT £5.83, pack of 14 tablets Excl VAT £9.99. Date: December 2015 


Citation: The Pharmaceutical Journal URI: 20201644

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Supplementary images

  • Nexium control pillbox
  • Product of the year 2016 logo
  • Duration of heartburn medications, from antacids, alginates, H2 Blockers to PPIs

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