Rachel Brazil is a science writer based in London, UK
Study results suggest that PDE-5 inhibitors could have a role in treating cancer, heart failure, neurodegenerative diseases, circulatory disorders and even infectious diseases, but the road to approval for new indications may not be smooth.
Smaller, smarter and more sensitive — how four new technologies could change the way drugs are monitored and administered.
Getting drugs across the blood-brain barrier could be key to developing more successful therapies to treat central nervous system disorders, such as Alzheimer’s disease, depression and epilepsy. Scientists are investigating a number of ways to achieve this, from using Trojan horses to smuggle drugs across the barrier, to temporary disruption of the barrier using ultrasound, to allow drugs into the brain.
Nocebo: the placebo effect’s evil twin Subscription
Photopharmacology: using light to activate drugsSubscription