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In the media

Dose adjustments for overweight patients

5 August 2014: The Daily Mail looked at whether GPs should be giving higher drug doses to patients who are obese. Royal Pharmaceutical Society (RPS) spokesman Steve Tomlin spoke to the newspaper and said that the weight of the patient needs to be considered when calculating doses. Referring to the fact that some drugs are fat soluble, Tomlin said: “Once absorbed, most drugs do not spread evenly throughout the body. Drugs that dissolve in water tend to stay within the blood and fluid surrounding cells, while fat soluble drugs tend to concentrate in fatty tissues. If you have a drug that goes into fats, someone who is obese may need to be given a dose based on their weight.”

Citation: The Pharmaceutical Journal DOI: 10.1211/PJ.2014.20066160

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