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Researchers are investigating whether priming the immune system with therapeutic vaccines can prompt the body’s own defences to spring into action against cancer.
Tracking down the optimum dose of exerciseSubscription
Prescribing physical activity could soon become as routine as prescribing drugs, and at least as beneficial.
Heroin abuse: breaking the cycleSubscription
With rates of heroin addiction stubbornly high, there is still debate about how best to treat those hooked on the drug.
Scientists are using systematic approaches to identify non-oncology drugs that can be used to treat cancer, but access to drugs and commercial challenges are hindering progress.
NHS England has launched an investigation into “extremely serious allegations” that health officials were paid to attend a trip hosted by a pharmaceutical company that may have influenced NHS use of the company’s product.
A judicial review against the Health Research Authority, challenging the steps it took to monitor the registration of clinical trials, has been upheld by a High Court judge.
Lloydspharmacy is to acquire Sainsbury’s pharmacy business for £125m, as part of a strategic partnership between the supermarket chain and Celesio AG announced on 29 July 2015.
A national service that reimburses pharmacists for providing emergency supplies of prescription medicines would boost patient care, research suggests.
The US Food and Drug Administration has approved sonidegib as a treatment for patients with locally advanced basal cell carcinoma.
The Medicines and Healthcare products Regulatory Agency has backed the continued use of the thrombolytic drug alteplase for up to 4.5 hours after the onset of symptoms of acute ischaemic stroke.
Patients who take glitazone drugs to manage their diabetes may have some protection from developing Parkinson’s disease, suggests new research.
The US Food and Drug Administration has approved alirocumab (Praluent), days after evolocumab (Repatha) became the first PCSK9 inhibitor to be approved in the world.
Two antimalarials were found to activate a receptor in the brain that is involved in protecting neurons that are lost in Parkinson’s disease.
Researchers have analysed health records of children in the UK and concluded that antibiotics may play a role in the pathogenesis of juvenile idiopathic arthritis.
Researchers conducted a randomised controlled trial of metformin in pregnant obese women, but the drug did not reduce the birthweight of offspring or pregnancy complications.
A systematic review and meta-analysis has concluded that benzodiazepines are ineffective in post traumatic stress disorder and that the risks “tend to outweigh” potential short-term benefits.
A London-based team, who helped reduce complications for patients with diabetes before and during surgery, were finalists in this year’s Pharmaceutical Care Awards.
A project in Northern Ireland has demonstrated the value of a consultant pharmacist reviewing medicines for patients in nursing homes.
High-risk patients from 70 care homes in London received personalised care plans from a multi-disciplinary project team.
Blood borne virus project wins ‘most reproducible’ audience vote at Pharmaceutical Care AwardsSubscription
The audience choice award was presented to a community pharmacy project that focused on testing for hepatitis B, hepatitis C and HIV in the Isle of Wight.
Ventmax SR capsules discontinuedSubscription
Chiesi has discontinued Ventmax (salbutamol sulphate) SR capsules 4mg and 8mg with immediate effect. Medical information is available on 0161 488 5555.
Astellas is discontinuing De-noltab (tri-potassium di-citrato bismuthate) tablets from 31 December 2015. De-noltab tablets will be available to order until 30 December 2015.
Disipal tablets discontinuedSubscription
Astellas is discontinuing Disipal tablets (orphenadrine hydrochloride) 50mg from 1 December 2015 because of manufacturing issues. Disipal can be ordered until 30 November 2015.
Arrhythmia with MoviprepSubscription
Arrhythmia has been added as an adverse event with unknown frequency to the summary of product characteristics (SPC) for Moviprep (macrogol, sodium sulfate anhydrous, sodium chloride, potassium chloride, ascorbic acid, sodium ascorbate; Norgine). Additionally, the SPC now states that two litres of Moviprep can be taken in the morning of a clinical procedure.
Acute coronary syndrome guidelineSubscription
The Scottish Intercollegiate Guidelines Network (SIGN) has published an updated draft guideline on acute coronary syndrome. The guideline is available for consultation on the SIGN website until 14 August 2015.
Kuvan (sapropterin dihydrochloride; Merck Serono) is now indicated for use in children with phenylketonuria under four years old who have shown to be responsive. The recommended method of administration in children up to 20kg has also been revised.
Extended indication for RelistorSubscription
Relistor (methylnaltrexone bromide; TMC Pharma Services) is now indicated for opioid-induced constipation when response to laxative therapy has not been sufficient in adults aged 18 years and older. Further changes to the summary of product characteristics reflect this license extension.
QT interval prolongation with ZytigaSubscription
Prolongation of the QT interval has been added as an adverse event with unknown frequency to the summary of product characteristics (SPC) for Zytiga (abiraterone; Janssen-Cilag). The updated SPC now advises caution when administering Zytiga with medicinal products known to prolong the QT interval or those able to induce torsade de pointes.