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moderate to severe psoriasis

FDA approves brodalumab for psoriasis with notice about risk of suicide

The US Food and Drug Administration (FDA) has approved an injectable biologic, brodalumab (Siliq), for psoriasis in adults that comes with a warning about the risk of suicide. 

Professor Colin Garner of Antibiotic Research UK

Antibiotic policies reduce unnecessary use in hospitals and cut lengths of stays

Antibiotic stewardship interventions are more effective if they contain enabling components, such as goal setting, feedback and action planning, say the authors of an updated Cochrane review.

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Beta-blockers risk functional decline in some older patientsSubscription

Nursing home residents with pre-existing cognitive or functional impairments were at a higher risk of functional decline after taking beta-blockers following acute myocardial infarction, study shows.

Close up of otitis media ear infection

Shortening antibiotic treatment worsens outcomes in children with ear infectionSubscription

Researchers found that standard-duration antibiotic treatment for acute otitis media works better than shorter treatments.

Close up of aspirin tablets

Non-aspirin NSAIDs outperform aspirin for colorectal cancer preventionSubscription

Non-aspirin NSAIDs offer protection against colorectal cancer but carry a high risk of adverse events.

Woman in wheelchair pushed by a man

Ocrelizumab cuts relapse rates and disability progression in MSSubscription

Researchers found ocrelizumab to be more effective than interferon beta-1a for treating relapsing MS

Chemotherapy drugs on tray

Modelling approach could optimise drug combination choiceSubscription

Researchers used polynomial modelling to simulate complex drug-dose effects and found that they could accurately predict the dose-effect function of drug combinations.

Micrograph of Zika virus particles

Antibodies from Zika patient protect mice against diseaseSubscription

Attempts to isolate human monoclonal antibodies (mAbs) against Zika virus have led to broadly neutralising antibodies that also show activity against Dengue virus.

More research briefings

Photopharmacology concept with light spectrum and switch

Photopharmacology: using light to activate drugsSubscription

 Drugs that contain synthetic light-switching molecules could help target therapies to particular parts of the body, limiting side effects. Researchers have started using this approach to tackle blindness, cancer, diabetes, and antibiotic resistance, but questions remain about the clinical practicality of the field.

Collage of the key players in the pharmacy funding cuts

Pharmacy funding cuts: the story so farSubscription

When the Department of Health revealed in December 2015 that it was planning to cut community pharmacy funding in England by 6%, shockwaves ran through the sector. Now, over a year later, community pharmacies are beginning to feel the impact.

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Special report

Summary care record

A one-off £200 payment will be awarded to each England-based community pharmacy contractor when the summary care record (SCR) service is activated before 31 March 2017, and pharmacies using the SCR can earn points through the Quality Payments scheme — which could be worth up to £1,280. Learn more about the service and how to use it with The Pharmaceutical Journal’s special report on the SCR.

Read on

Closed pharmacy store

Latest update: Follow news and reaction to pharmacy cuts as they unfold

Follow the latest updates on the proposed 12% funding cuts to community pharmacy, which could result in the closure of a quarter of pharmacies in England.

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A reference you need

Introduction to Pharmaceutical Calculations

Together with its companion text Pharmaceutical Calculations Workbook, Introduction to Pharmaceutical Calculations is essential reading for pharmacy undergraduates and pre-registration pharmacists.

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