Oseltamivir (Roche’s Tamiflu) shortens the duration of flu symptoms by approximately a day, in infected patients, according to an analysis published in The Lancet.
The European Commission has authorised apremilast (Celgene’s Otezla), a first-in-class oral drug for the treatment of chronic plaque psoriasis and psoriatic arthritis in patients who have failed first-line systemic therapies.
Treatment perceived to be expensive, even though it was a placebo, led to a two-fold improvement in motor function in Parkinson’s disease patients compared with a treatment perceived to be cheap.
European drug manufacturers have developed a communications framework which they claim could help prevent medicines shortages or lessen their impact.
People aged over 65 years who take some common over-the-counter or prescribed medicines for allergy, depression or an overactive bladder have an increased risk of developing dementia.
The European Medicines Agency is recommending that the marketing authorisation be suspended for more than 700 generic products manufactured by GVK Biosciences.
Researchers studying endometriosis have discovered a potential way to treat the disease that avoids many of the side effects seen with existing therapies.
The European Medicines Agency is recommending that the prescription-only injectable drug liraglutide (Saxenda) should be granted a marketing authorisation as a weight loss product.
People who have daily heartburn for three consecutive weeks may be at risk from oesophageal or stomach cancer and are advised to visit their GP, according to a new public health campaign.
Human Protein Atlas reveals drug targetsSubscription
The Human Protein Atlas shows the locations of almost 17,000 different proteins in the human body and could offer invaluable guidance for drug developers.
A highly effective therapy for patients with hepatitis C is being launched by AbbVie in the EU over the next couple of months in direct competition with another treatment made by Gilead that was approved in 2014 and is now being rolled out.
Precision medicine got a shot in the arm on 20 January 2015, when US President Barack Obama launched a Precision Medicine Initiative to help cure diseases like cancer and diabetes.
Patients with type 2 diabetes are more likely to take their medicines as prescribed if they are male, have a degree and earn more than US$60,000 dollars a year.
Some 41.5% of US adults who drink alcohol report taking medicines known to interact with alcohol, according to research published in Alcoholism: Clinical and Experimental Research.
The cost of vaccines recommended by the World Health Organization has gone up 68-fold over the past 13 years, according to international aid charity Médecins sans Frontières.
WHO calls for basic medicines to be made available to tackle deaths from non-communicable diseasesSubscription
Just under half the 38 million deaths in the world from non-communicable diseases could have been prevented, according to the World Health Organization.
A new medicine that allows Parkinson’s disease patients to spend more of the day symptom-free has been recommended for approval in Europe.
A drug approved for the treatment of attention deficit-hyperactivity disorder, lisdexamfetamine dimesylate, cuts the number of binge eating days in people with binge eating disorder, according to a study.
Continued access to innovative treatments and improved prevention strategies will allow cancer deaths in people under 80 years of age to be eliminated by 2050.
Increased risk of severe skin reactions with expectorants containing ambroxol or bromhexineSubscription
Patients taking expectorants containing ambroxol or bromhexine have a small increased risk of severe skin reactions such as Stevens-Johnson syndrome.
The speed at which smokers metabolise nicotine may suggest the most effective smoking cessation method – either varenicline or the nicotine patch.
Shire has announced a US$5.2bn acquisition of the US company NPS Pharmaceuticals following unanimous approval by both company boards.
Analysis finds the long acting birth control injection could increase the risk of HIV infection in women, with the highest risk observed in sex workers.
Counselling and lifestyle changes could be better used to treat headaches rather than relying on advanced imaging tests and specialist referrals.
The US Food and Drug Administration (FDA)’s oncologic drugs advisory committee has given the green light to Sandoz’s EP2006, a biosimilar version of filgrastim.
Bursts of testosterone can curb prostate cancer that has spread to other parts of the body, according to a small clinical trial.
Researchers using an innovative process have discovered a new antibiotic with properties that appear to prevent the development of resistance.
Anaesthetists campaign for pholcodine cough medicines to become prescription-only productsSubscription
Anaesthetists in Australia and New Zealand are campaigning for pholcodine-containing cough medicines to become prescription-only products.
Scientists have developed a drug that curbs weight gain and corrects the metabolic defects associated with obesity without reducing food intake.
Moorfields Eye Hospital NHS Foundation Trust has decided to close its specials manufacturing facility in London, its board has announced.
Eculizumab, dubbed “the world’s most expensive drug”, is being made available on the NHS in England following guidance from the National Institute for Health and Care Excellence.
Pre-reg pharmacists dissatisfied with their training more likely to have trained in community sectorSubscription
Pharmacist trainees who completed their training in the community sector are more likely to be dissatisfied with the experience, while a higher proportion of dissatisfied students trained in London.
A new model of pharmacy in North East LondonSubscription
North East London Local Pharmaceutical Committee is recruiting pharmacies to take part in its new ‘SelfCare Pharmacy’ practice. Will its efforts result in a viable new model of pharmacy care?
Women taking valproate should be told about risks of developmental disorders in offspringSubscription
Women taking valproate should be told about the risks of developmental disorders in children exposed to the drug during pregnancy, says the UK medicines regulator.
Many patients taking non-steroidal anti-inflammatory drugs are not co-prescribed gastroprotective agents, an audit of community pharmacies in England has found.
The Cancer Drugs Fund has undermined the National Institute for Health and Care Excellence and has provided a “get out of jail card” for pharmaceutical companies, its chair says.
NHS England has postponed plans for community pharmacists to name their pharmacy when they report patient safety incidents until after the law is changed to decriminalise dispensing errors.
Sofosbuvir has received the green light from NICE but will not be available to patients until August 2015, while simeprevir will only be accessible through a patient access scheme.
The National Institute for Health and Care Excellence has published its first clinical guideline on the management of gastro-oesophageal reflux disease in infants and children.
The public trusts pharmacists but not to the same degree as other health professionals, survey showsSubscription
The public trusts the advice given by a community pharmacist but the degree of trust is lower than that afforded to other health professionals, according to an IPSOS/Mori poll.
Oral diclofenac tablets, used for short-term pain relief, will no longer be available as an over-the-counter pharmacy medicine in the UK.
The second once-weekly non-insulin injection for patients with type 2 diabetes became available in the UK from 13 January 2015.
A total of 25 clinical indications will be removed from the government’s cancer drugs fund list, NHS England has announced.
In a study of 15,000 adults, those who consumed up to seven drinks per week in early-to-middle age had a significantly lower risk of developing heart failure compared with their teetotal counterparts.
A survey of nearly 70,000 patients taking aspirin for primary prevention has found that, for the overall cohort, treatment was inappropriate in nearly 11.6% of cases.
IRAK-M, a key negative regulator of inflammatory pathways, may represent a new therapeutic target to suppress bacteria-induced inflammation, say researchers.
In 25 placebo-controlled trials involving nearly 47,000 patients, adverse cognitive outcomes attributable to statins were rarely reported, researchers found.
Population-wide approaches to risk-factor control have had a far greater impact on the reduction of deaths from coronary heart disease than use of primary prevention medication.
Use of non-steroidal anti-inflammatory drugs (NSAIDs) in patients undergoing surgery may be associated with anastomotic leak at the surgical junction, research confirms.
A tattoo-based iontophoresis-sensor platform holds considerable promise for efficient diabetes management, say researchers.
ATR inhibition may be a useful treatment approach in cancers that use the alternative lengthening of telomeres (ALT) pathway to overcome cell death.