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Developing new psoriasis treatment regimens for patients based on their clinical profileSubscription
Biologics and small-molecule drugs being developed to treat psoriasis are showing encouraging results, but high costs could limit their use.
Placebos: more than meets the eyeSubscription
Often dismissed as fakes, placebos seem to work on the same brain pathways targeted by ‘real’ treatments and involve a complex network of genes.
Asthma therapies get personalSubscription
A new crop of biologic drugs promises to usher asthma treatment into the realm of personalised medicine.
Closing in on Alzheimer’s diseaseSubscription
Knowledge about the neuropathology of Alzheimer’s disease has blossomed over the past few decades, leading to a better understanding of the condition and new ways to attack it.
Pembrolizumab (Keytruda) has been recommended for use as a melanoma treatment in England by the National Institute for Health and Care Excellence.
A report from NHS Alliance and the Primary Care Foundation estimates 5.5% of family doctor appointments could be dealt with by a pharmacist.
The NHS health check programme is ineffective and wastes £450m a year that could be better spent promoting healthy eating, according to research published in the Journal of Public Health.
Women in the UK will be able to self-administer an injectable contraceptive for the first time after the medicines regulator approved new labelling for Sayana Press.
UK pharmacists receive international awardsSubscription
Two UK academic pharmacists have been honoured with awards at the opening ceremony of the International Pharmaceutical Federation 2015 annual congress in Dusseldorf, Germany.
Pregnant women who have cancer do not necessarily need to have a termination for fear of the harm their treatment will cause a developing baby, study finds.
Colds, flu and other minor infections may temporarily raise the risk of stroke in children, while routine childhood vaccinations may reduce the risk, according to research published in Neurology.
A study of more than 12,000 infants found that those who have used inhaled corticosteroids to treat asthma up to the age of two years are more likely to be short for their age.
An international study found that giving patients higher but fewer doses of radiotherapy was as effective as standard radiotherapy for prostate cancer.
Pancreatic beta cells destroyed in type 1 diabetes could be replaced with other pancreatic cells reprogrammed to produce insulin, suggests study
Over the past 30 years, more drugs qualified for accelerated approval programmes with the FDA despite not being first-in-class medicines.
Data from 4.1 million patients in the UK found that high blood pressure was indepdendently associated with an increased risk of developing diabetes.
Pilot highlights ‘massive need’ for clinical pharmacist input into dispensing GP practicesSubscription
Findings from a pilot, in which a pharmacist independent prescriber provided face-to-face medication reviews in two dispensing practices, suggest that such care can deliver many benefits to patients.
The evidence derived from a scheme to place pharmacists in general practice to ease pressures on GPs in England will be crucial to further integrating pharmacists into primary care, according to a leading practice pharmacist.
The pharmacy workforce must embrace clinical practice in the next few years amid advancements in medical and dispensing technologies, according to the UK’s chief pharmaceutical officers.
Point of care tests are one of the most crucial developments in the fight against antimicrobial resistance, according to a leading antimicrobial pharmacist.
Hypnomidate handling recommendationsSubscription
The summary of product characteristics for Hypnomidate (etomidate; Janssen) now recommends that gloves are worn when opening the ampoule, in order to avoid accidental exposure to the skin. Other changes include an update to the drug’s effect on fertility, pregnancy and lactation, among other amendments.
Indivina adverse events updated Subscription
The summary of product characteristics for Indivina (estradiol valerate and medroxyprogesterone acetate; Orion Pharma) has been updated in line with core texts for hormone replacement therapies. It now states that adverse events such as myocardial infarction and gall bladder disease have been reported in association with hormone treatments, among other changes.
Biosimilar medicines resourceSubscription
NHS England has published a document entitled ‘What is a biosimilar medicine?’, which explains how healthcare professionals can support the appropriate use of all biological medicines, including biosimilar medicines, for the benefit of NHS patients. The NHS England document, which was produced in collaboration with the Medicines and Healthcare product Regulatory Agency, the National Institute of Health and Care Excellence, the Royal Pharmaceutical Society and the pharmaceutical industry ...
New indication for VenoferSubscription
Venofer (iron sucrose; Vifor) solution for injection or concentrate for solution for infusion is now indicated for the treatment of iron deficiency in individuals with chronic kidney disease when oral iron preparations are less effective than Venofer.
Ketalar out of stockSubscription
Ketalar (ketamine hydrochloride) injection 50mg/ml 10ml is currently out of stock from Pfizer. The company anticipates that supply will resume in late October or early November 2015. For further supply information, call 0845 6088866. For medical information, call 01304 616161.
Daklinza for HIV co-infected patientsSubscription
The summary of product characteristics of Daklinza (daclatasvir; Bristol-Myers Squibb) has been updated to reflect the results of a study, which found the medicine is effective at treating hepatitis C when patients are also infected with HIV. This includes changes to the posology and information on interactions with other medicines.
Otezla rejected by NICESubscription
The National Institute for Health and Care Excellence has issued final guidance not recommending Otezla (apremilast; Celgene) for the treatment of moderate to severe plaque psoriasis in the NHS in England and Wales. This is because the medicine is not considered to be cost-effective.
Pictogram software available from FIPSubscription
The International Pharmaceutical Federation (FIP) has published an Arabic version of its pictogram software to help pharmacists explain to refugees how to take their medicines. The pictogram software is available from the FIP website.