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Primary prevention of cardiovascular disease with statins: assessing the evidence base behind clinical guidanceSubscription
Statins and other cholesterol-lowering drugs are increasingly being used for primary prevention of atherosclerotic cardiovascular disease. Three lines of evidence inform the development of therapeutic goals for both drug and lifestyle intervention. This evidence reveals the following principles for cholesterol lowering in primary prevention: (a) ‘the more (lowering), the better’ for relative risk reduction, (b) ‘the lower, the better’ for absolute risk reduction, and (c) ‘the earlier, ...
Considerations in selecting pharmacological treatments for attention deficit hyperactivity disorder Subscription
Attention deficit hyperactivity disorder (ADHD) is highly prevalent and is associated with significant impairment across the lifespan. Medication treatments, particularly stimulant medications, are important in the management of ADHD, although non-medication treatments (e.g. therapy to improve organisational, social and emotional regulation skills) are often also needed. The stimulant medications have a high response rate and improve the core symptoms of the disorder, but they are ...
Antiepileptic drug safety in pregnancy: possible dangers for the pregnant woman and her foetusSubscription
In addition to the safety issues that apply whenever antiepileptic drugs are taken by patients, additional safety-related matters arise in pregnant women. These may involve the women themselves or their foetuses, and apply both during, and for a time after, pregnancy. During pregnancy, the safety of women with epilepsy may be endangered by loss of seizure control caused by increased antiepileptic drug clearances not being compensated for by appropriate adjustments of drug dosages. ...
Acute insomnia was resolved following a one-hour therapy session in over 70% of cases, according to a UK-based study.
Drug safety was a hot topic in 2015, accounting for five of the top 10 news stories consumed by our readers.
Foods that cause blood glucose spikeSubscription
Serious side effect with quinolone antibioticsSubscription
No mention of pharmacistsSubscription
Cyramza indication extendedSubscription
Revolade for idiopathic ITPSubscription
Desmopressin patient safety alertSubscription
NICE recommends nintedanibSubscription
NICE does not recommend ramucirumabSubscription
NICE recommends panobinostatSubscription
NICE recommends prostate cancer drugsSubscription
NICE recommends olaparibSubscription