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Review article

Statins and other cholesterol-lowering drugs are increasingly being used for primary prevention of atherosclerotic cardiovascular disease. In the image, micrograph of cholesterol crystals

Primary prevention of cardiovascular disease with statins: assessing the evidence base behind clinical guidanceSubscription

12 FEB 2016By

Statins and other cholesterol-lowering drugs are increasingly being used for primary prevention of atherosclerotic cardiovascular disease. Three lines of evidence inform the development of therapeutic goals for both drug and lifestyle intervention. This evidence reveals the following principles for cholesterol lowering in primary prevention: (a) ‘the more (lowering), the better’ for relative risk reduction, (b) ‘the lower, the better’ for absolute risk reduction, and (c) ‘the earlier, ...

Inattention and hyperactive/impulsive symptoms are commonly seen in practice, with up to 6% of children meeting criteria for attention deficit hyperactivity disorder (ADHD). In the image, a crying child looks at the camera

Considerations in selecting pharmacological treatments for attention deficit hyperactivity disorder Subscription

11 FEB 2016By ,

Attention deficit hyperactivity disorder (ADHD) is highly prevalent and is associated with significant impairment across the lifespan. Medication treatments, particularly stimulant medications, are important in the management of ADHD, although non-medication treatments (e.g. therapy to improve organisational, social and emotional regulation skills) are often also needed. The stimulant medications have a high response rate and improve the core symptoms of the disorder, but they are ...

The safety of antiepileptic drug use in pregnancy involves: the pregnant woman in her own right; the foetus while in her womb; and during its subsequent extra-uterine existence as a neonate and infant. Pregnant woman during an ultrasound scan pictured

Antiepileptic drug safety in pregnancy: possible dangers for the pregnant woman and her foetusSubscription

15 JAN 2016By

In addition to the safety issues that apply whenever antiepileptic drugs are taken by patients, additional safety-related matters arise in pregnant women. These may involve the women themselves or their foetuses, and apply both during, and for a time after, pregnancy. During pregnancy, the safety of women with epilepsy may be endangered by loss of seizure control caused by increased antiepileptic drug clearances not being compensated for by appropriate adjustments of drug dosages. ...

Two months on from the announcement that the community pharmacy contractual framework will be cut by 6% in 2016, Sandra Gidley, chair of the RPS English Pharmacy Board, talks about the proposed changes and what the RPS is doing

Making the case for community pharmacy Subscription

9 FEB 2016By

Two months on from the announcement that the community pharmacy contractual framework will be cut by 6% in 2016, Sandra Gidley, chair of the RPS English Pharmacy Board, talks to Julia Robinson about her thoughts on the proposed changes and what the RPS is doing to support its members through them.

All Cuts to community pharmacy funding in England

Special report

Care of older people

Care of older people

Old age brings with it an increased likelihood of long-term conditions, as well as the prospect of taking multiple medicines. Frailty, dementia and mobility problems all contribute to the challenges faced by healthcare services when caring for ageing populations. Much can be done to improve the lives of older people – through innovative care pathways, evidence-based medicine and research into ageing and the delivery of care. Here, you can find news stories and articles on topics ranging from medication reviews in care homes to preventing falls in older people.

Read on

A reference you need

British National Formulary, 70th edition

Up-to-date, practical guidance on prescribing, dispensing, administering medicines and current best practice relating to the uses of medicines, as well as legal and professional guidelines.

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