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Micrograph of human skin

Atopic dermatitis: dupilumab and crisaborole could herald a new era in treatmentSubscription

Atopic dermatitis can have a devastating effect on quality of life, but there have been no major changes to the way it has been treated for over 15 years. Now, two new therapies — dupilumab, a biologic for severe disease, and crisaborole, a topical small molecule drug for milder disease — could herald a new era in the treatment of this distressing condition.

Infographic showing how dupilumab works

Atopic dermatitis: emerging and current treatments Subscription

Atopic dermatitis affects up to 30% of children and 10% of adults, and is common in both developed and developing countries. Two new medicines on the brink of entering the market — dupilumab, a biologic for severe disease, and crisaborole, a topical small molecule drug for milder disease — could herald a new era in the management of this condition, which has seen no major changes to the way it has been treated for over 15 years.

Signing of the agreement between Manchester health service and the pharmaceutical industry

Manchester could pay for medicines based on efficacy

The health service in Manchester has signed a deal with the pharmaceutical industry that could lead to the authorities paying for medicines based on their efficacy.

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Amniocentesis

Preconception care: genetic and pre-existing conditionsSubscription

Pharmacists and healthcare professionals can provide appropriate and comprehensive preconception care by identifying couples who are at risk of having a baby with a genetic or chromosomal malformation and can empower the couple by giving them enough knowledge to make informed decisions.

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Roger Humbles, community pharmacist and owner of Fourway Pharmacy

How community pharmacy owner Roger Humbles became the face of a media campaignSubscription

As a community pharmacist, Roger Humbles is aware of the increased levels of illness, deaths and pressure on the NHS in winter. Here, he talks about publicity and running his own pharmacy.

Sophie Riddell with a client

How pharmacists can become aesthetic practitionersSubscription

As demand for non-surgical cosmetic procedures increases, Saša Jankovic finds out about training requirements, industry regulation, as well as the benefits pharmacists can provide patients by offering these services.

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Faculty handbook for pharmacists on the CPPE general practice pharmacist training pathway

RPS and CPPE launch Faculty handbook for practice-based pharmacistsSubscription

The Royal Pharmaceutical Society (RPS) and Centre for Pharmacy Postgraduate Education (CPPE) have published a Faculty handbook for pharmacists on the CPPE general practice pharmacist training pathway (GPPTP), ...

More Your RPS

Micrograph of human skin

Atopic dermatitis: dupilumab and crisaborole could herald a new era in treatmentSubscription

Atopic dermatitis can have a devastating effect on quality of life, but there have been no major changes to the way it has been treated for over 15 years. Now, two new therapies — dupilumab, a biologic for severe disease, and crisaborole, a topical small molecule drug for milder disease — could herald a new era in the treatment of this distressing condition.

Pharmacist and patient in a pharmacy consultation room

The Murray review: moving in the right directionSubscription

On 20 December 2016, six days after the long-awaited report by the King’s Fund’s Richard Murray on the provision of clinical services in community pharmacy was published, health minister David Mowat described the review as “an essential road map that sets out how we are going to move the community pharmacy network away from a remuneration model”.

Photopharmacology concept with light spectrum and switch

Photopharmacology: using light to activate drugsSubscription

 Drugs that contain synthetic light-switching molecules could help target therapies to particular parts of the body, limiting side effects. Researchers have started using this approach to tackle blindness, cancer, diabetes, and antibiotic resistance, but questions remain about the clinical practicality of the field.

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Special report

Summary care record

A one-off £200 payment will be awarded to each England-based community pharmacy contractor when the summary care record (SCR) service is activated before 31 March 2017, and pharmacies using the SCR can earn points through the Quality Payments scheme — which could be worth up to £1,280. Learn more about the service and how to use it with The Pharmaceutical Journal’s special report on the SCR.

Read on

White Paper

Headaches in children: An unmet need

Pharmacist Christine Glover discusses the need for greater awareness and better management of paediatric headache in community pharmacy.

This article was commissioned, briefed and fully funded by RB.

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Donald M. Berwick

Q&A: Invest in safety and make savings overall — interview with Don BerwickSubscription

The author of the 2013 report which looked at patient safety in the NHS after the Mid Staffordshire Hospital scandal speaks to Jenny Bryan to share his thoughts on whether progress has been made.

Your RPS needs youSubscription

Show your passion and dedication to pharmacy by putting yourself forward for this year’s RPS national pharmacy board elections.

More opinion

Infographic showing how dupilumab works

Atopic dermatitis: emerging and current treatments Subscription

Atopic dermatitis affects up to 30% of children and 10% of adults, and is common in both developed and developing countries. Two new medicines on the brink of entering the market — dupilumab, a biologic for severe disease, and crisaborole, a topical small molecule drug for milder disease — could herald a new era in the management of this condition, which has seen no major changes to the way it has been treated for over 15 years.

More infographics

Micrograph of Clostridium difficile bacteria

Clostridium difficile: diagnosis and treatment update

There are around 12,000 cases of Clostridium difficile infection (CDI) each year in the UK and during 1999 to 2007, deaths from CDI peaked at around 4,000 per year. This article summarises diagnosis and management, as well as the current therapeutic options for CDI, including faecal microbiota transplant.

coloured scanning electron micrograph (SEM) of bacterial blood infection (sepsis) caused by a rod shaped bacterium (blue)

Sepsis: an update on identification and management Subscription

All healthcare professionals, including pharmacists, should be aware of the clinical features and management of sepsis. This article summarises the recent changes in the definition of sepsis in adults, as well as its management.

More CPD modules

The rise of patient-centred technologies in community pharmacy

2017 could see a rise in patient-centred technologies across pharmacy. Martin Hao, managing director at Healthera, a new medicines management app, looks at the reasons behind the trend.

Brexit illustration with divided euro coin on European map

Preserving research and development in a post-Brexit era

Additional funding for R&D post-Brexit is a welcome move from the UK government, but there are other related issues to consider as well.

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Cover of the book "Introduction to drug disposition and pharmacokinetics"

Basic introduction to knowledge and skills required in new drug developmentSubscription

Introduction to drug disposition and pharmacokinetics, by Stephen H Curry and Robin Whelpton

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Research article

Molecular model of C-reactive protein

Evaluating a point-of-care C-reactive protein test to support antibiotic prescribing decisions in a general practiceSubscription

Abstract Background: C-reactive protein (CRP) is a marker of infection and inflammation. It is high in bacterial infections but very low or close to zero in viral infections. The National Institute for Health and Care Excellence (NICE), England and Wales’s health technology assessment body, has issued guidance on pneumonia in adults; it recommends point-of-care (POC) CRP analysers when clinical assessment is inconclusive. If the CRP level ...

Oral anticoagulant therapy and INR blood test monitor

Assessing the impact of a targeted pharmacist-led anticoagulant review clinicSubscription

Abstract Background: Local guidance, supported by the 2014 National Institute for Health and Care Excellence (NICE) guideline CG180 for atrial fibrillation (AF), recommends that patients receiving inadequate anticoagulation with a vitamin K antagonist (VKA), including time in therapeutic range (TTR) of <65%, should be reassessed. These patients were identified by the anticoagulation monitoring service (AMS) and highlighted to GPs for review. ...

Close-up of a person taking a dry-blood spot test

Integrating community pharmacy testing for hepatitis C with specialist careSubscription

Abstract Background:  Many patients with hepatitis C virus (HCV) infection lie undiagnosed and a significant proportion of patients that have been identified are disengaged from specialist services. The Isle of Wight (IOW) typifies this issue, with an estimated 200 undiagnosed patients with HCV infection and a small number of known cases engaged with specialist services. Aim:  To reduce the burden of undiagnosed HCV ...

NHS pharmacist discusses patient care with a nurse on a ward

Examining the emerging roles for pharmacists as part of the urgent, acute and emergency care workforceSubscription

By , , , ,

Abstract In the future urgent, acute and emergency medicine clinical workforce, new models of care and care delivery need to be developed, in order to maintain and enhance standards of safe and accessible patient care. A departure from traditional (doctor-led) approaches to workforce planning, and an understanding of scope and governance surrounding emerging clinical roles is necessary to develop a sustainable, multi-skilled workforce across primary, community and secondary ...

More perspective articles

Image 1 shows a normal spine and image 2 shows a spine affected by spondylitis

TNFα-inhibitors for ankylosing spondylitis and non-radiographic axial spondyloarthritisSubscription

By , , , , , , , , ,

Abstract Spondyloarthropathy refers to a group of articular inflammatory diseases that share common genetic, clinical and radiological features in addition to their association with human leucocyte antigen (HLA)-B27 antigen. The aim of therapeutic management of patients with spondyloarthritis is to improve quality of life, control the symptoms of articular inflammation, prevent the structural damage of joints, and preserve the functional abilities, autonomy and social participation ...

More review articles

A reference you need

British National Formulary, 71st edition

Up-to-date, practical guidance on prescribing, dispensing, administering medicines and current best practice relating to the uses of medicines, as well as legal and professional guidelines.

Order your copy

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