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Coloured 3D computed tomography (CT) scan of the abdomen of a patient with impacted bowels, which could occur in patients with untreated constipation

Constipation: managing the condition in adultsSubscription

How to assess patients with constipation and select the right treatment to minimise the risk of complications.

Rain pouring down on Mt Hood National Forest in Oregon, USA

The secret life of ketamineSubscription

Ketamine is being used to treat depression in clinics that are springing up across the United States, but uncertainty remains over its long-term use.

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Complete the CPD modules and receive your certificate from The Pharmaceutical Journal.

Dialysis involves passing the patient’s blood against a semi-permeable membrane. The main options are haemodialysis (HD) pictured, using a dialysis machine and peritoneal dialysis (PD), which uses the patient’s peritoneum

Dialysis: principles and treatment optionsSubscription

How to choose between haemodialysis and peritoneal dialysis when starting renal replacement therapy.

Patients with end-stage renal disease require renal replacement therapy, such as dialysis, to replace the function of the kidneys. Patients will require clinical management to provide a number of small functions. In the image, a patient receives dialysis

Dialysis: managementSubscription

How to identify and manage potential complications and challenges presented by haemodialysis and peritoneal dialysis.

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In the image, a colour x-ray of a coronary artery with Kawasaki disease, a type of vasculitis. Vasculitis is a collection of rare diseases characterised by the inflammation of blood vessel walls.

Managing ANCA-associated vasculitisSubscription

Treatment of vasculitis associated with antineutrophil cytoplasmic antibodies requires immunosuppressive therapies and close monitoring of the patient to manage toxicity.

X-ray of deep vein thrombosis, pictured. Low molecular weight heparins (LMWHs) are used widely for the prophylaxis and treatment of venous thromboembolism (VTE).

Low molecular weight heparins for treating venous thromboembolismSubscription

How to start patients on these common injected anticoagulants and optimise treatment.

Inhaled corticosteroids (ICSs) are indicated in the management of most patients with asthma and some patients with chronic obstructive pulmonary disease (COPD). In the image, a scanning electron micrograph (SEM) showing alveoli and pulmonary blood vessels

Inhaled corticosteroids: managing side effectsSubscription

Inhaled corticosteroids are commonly prescribed but need careful management to minimise the risk of side effects.

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‘A scientist in wonderland: a memoir of searching for truth and finding trouble’, by Edzard Ernst

The troublesome truth about complementary and alternative medicinesSubscription

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‘A scientist in wonderland: a memoir of searching for truth and finding trouble’ by Edzard Ernst.

Mario Raviglione, director of the WHO’s Global TB Programme, discusses the tasks and challenges ahead

Mario Raviglione: an ambitious new strategy to end tuberculosisSubscription

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To coincide with World Tuberculosis Day on 24 March, the World Health Organization has called for support to achieve an ambitious new 20-year strategy to end the tuberculosis epidemic by 2035. Mario Raviglione, director of the WHO’s Global TB Programme, discusses the tasks and challenges ahea

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From July 2014, all employees with 26 weeks’ continuous employment are now able to submit a flexible working request

How changes to UK flexible working laws affect pharmacistsSubscription

Kevin McKenna, head of employment law at Kuits Solicitors in Manchester, explains how changes to laws on flexible working have affected employers and employees.

Pharmacists were able to apply for a clinical doctoral research Fellowships from the National Institute for Health Research for the first time in 2014, giving them access to funding for an applied healthcare project.

How to secure funding from the National Institute for Health ResearchSubscription

Pharmacists were able to apply for clinical doctoral research Fellowships from the National Institute for Health Research for the first time in 2014, giving them access to funding for an applied healthcare project. With applications for 2015 now open, experts on the process share their advice.

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David Branford is the English Pharmacy Board chair

RPS chair: GP practice role will help develop clinical future for the professionSubscription

Creating opportunities in general practice for pharmacists will allow to the profession to adopt a greater clinical role in care, says the English Pharmacy Board chair David Branford.

Bruce Warner, deputy chief pharmaceutical officer, said “the time is right” for more pharmacists to work as part of GP practice teams across the country

NHS England calls for assessment of pharmacists' skills for GP practice roleSubscription

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Deputy chief pharmaceutical officer warns NHS not to introduce pharmacists in GP surgeries initiative in a “reckless” manner, and says skills and training requirements must be assessed first.

Your RPS

NHS funding provided to GPs for them to deliver travel health services to their patients could be shifted to community pharmacy, according to a travel health expert

GP travel health funding could shift to pharmacySubscription

NHS funding provided to GPs for them to deliver travel health services to their patients could be shifted to community pharmacy, according to a travel health expert.

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The use of antipsychotic drugs in people with dementia poses a higher mortality risk than previously identified, and the risk increases with dose, study finds

Greater risk of death by antipsychotics in dementia patients, research suggestsSubscription

The risk of death caused by use of antipsychotic drugs in people with dementia is greater than previously thought, and increases in line with dose, research suggests.

Taking macrolide antibiotics, such as erythromycin and clarithromycin, during pregnancy could increase the risk of babies being born with epilepsy or cerebral palsy, report researchers from the UCL Institute of Child Health (ICH) in London

Study links use of macrolide antibiotics in pregnancy to infant epilepsy and cerebral palsy Subscription

A slightly increased risk of epilepsy or cerebral palsy for babies whose mothers take macrolide antibiotics during pregnancy has been found by UCL researchers.

US consumers prefer generic over branded drugsSubscription

Over 80% of US consumers say they would purchase generic drugs more often than brand name drugs and 42% said they would “always” choose a generic.

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Regulator seeks information on link between birth defects and hormonal pregnancy testsSubscription

The MHRA is calling for information that will help establish whether there is a link between the hormonal pregnancy test used in the 1960s and 1970s and birth defects.

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Hormone replacement therapy (HRT), pictured, has little if any benefit in the prevention of cardiovascular disease and causes an increase in the risk of stroke and venous thromboembolic events

HRT linked with increased stroke risk, conclude Cochrane reviewersSubscription

HRT has little if any benefit in the prevention of cardiovascular disease and causes an increase in the risk of stroke and venous thromboembolic events.

Several studies have found that statin therapy slightly increases the risk of new-onset type 2 diabetes. In the image, a woman takes a glucose test

Finnish study explores association between statin use and diabetesSubscription

Researchers have shown that statin use increases the risk of type 2 diabetes and suggest that the higher risk is due to decreases in insulin sensitivity and insulin secretion.

Specific immune-mediated mechanisms may define a biological subgroup within psychosis. Blood tests revealed antibodies to the dopamine (polarised micrograph pictured) D2 receptor in children with a first episode of psychosis

Psychosis may have immune-mediated cause, study suggestsSubscription

A study of children with a first episode of psychosis reveals that a subset produced specific autoantibodies, supporting the involvement of immune-mediated mechanisms.

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A pharmacist's journey through the Ebola epidemic

Pharmacist Claire Liew is currently volunteering at an Ebola treatment centre in Sierra Leone. She explains how the disease has affected everyday life.

Annoying noises and sound sensitivity

People with misophonia experience negative emotions when they hear specific sounds. Separately, phonophobia is the fear of loud sounds.

Swedish men can thank snus for health

Swedish men have the lowest level of tobacco-related deaths in Europe. This is likely to be due to their preference for low-nitrosamine oral tobacco (snus) over cigarettes.

The risks and benefits of eating seafood

Although eating fish is considered part of a healthy diet, Steve Bremer explains that consuming certain shellfish does come with its own risks.

Lady in the Bar from Group of 70 Police Photographs at ‘Forensics: the anatomy of crime’, at the Wellcome Collection, London

Dissecting forensics: review of an exhibition

A new exhibition, ‘Forensics: the anatomy of crime’, at the Wellcome Collection, London, aims to examine the forensic procedure from the crime scene to the courtroom. Emma Page takes a look.

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We need to accredit pre-registration tutors Subscription

I am writing in response to the General Pharmaceutical Council’s (GPhC) overhaul of the registration assessment from June 2016. Having attended the GPhC’s stakeholder’s event in London on 3 March 2015, I liked what I saw with respect to the changes being proposed. This change is, indeed, long overdue and the trainees will have to move away from a surface learning approach, where the skill is to search and find information, to a deeper approach where they have to apply the information ...

Pharmacists working in GP surgeries is an opportunity, not a threatSubscription

The Royal College of General Practitioners and the Royal Pharmaceutical Society have launched an exciting initiative where pharmacists will be working in GP surgeries (The Pharmaceutical Journal 2015;294:353). ...

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Reader's comment

NHS England have had 2 years to undertake an impact assessment, so there's small chance of them doing it over the next 2 weeks remaining. Central NHSE support for the various Area Teams, who have inherited LPS since they are not national contracts, has been conspicuous in its absence. As a result, the ATs themselves seem to be winging it as best they can, and existing LPS contractors are actually doing the research work NHSE should have done, as part of their new contract proposals.

Nick Ford RPS warns NHS England over withdrawal of funding for small pharmacies