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The search for alternative treatments to Mycobacterium tuberculosis has found positive results in the antidiabetic drug metformin

Metformin shows promise as anti-tuberculosis drugSubscription

A promising candidate in the search for alternative treatments for Mycobacterium tuberculosis is the antidiabetic drug metformin.

Immune checkpoint inhibitors - PD-1 and PD-L1- induce higher response rate across worst cancer tumours such as lung cancer

Immune checkpoint inhibitors bring new hope to cancer patientsSubscription

PD-1 and PD-L1 inhibitors induce a higher response rate across a wider range of tumours than other immunotherapies.

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Complete the CPD modules and receive your certificate from The Pharmaceutical Journal.

Giardia protozoan parasite (pictured) is the cause of the giardiasis infection, usually contracted by drinking contaminated water

Assessing suspected food poisoning cases in the UKSubscription

With more than 20,000 patients hospitalised in the UK each year due to food poisoning, quick assessment is essential.

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Pipeline November 2014Subscription

The latest approvals and positive opinions from the European Medicines Agency.

Pathology specimen of Crohn's disease (pictured) is a condition of inflammatory bowel disease (IBD)

Optimising therapy for inflammatory bowel diseaseSubscription

How to tailor treatment for patients and ensure optimum management of Crohn’s disease and ulcerative colitis.

Growing antimicrobial resistance is growing and results in 25,000 deaths in Europe each year. In the image, enterobacteriaceae (CRE) bacterium in an antibiotic susceptibility test proved to be resistant to all of the antibiotics tested

Improving antimicrobial stewardshipVideoSubscription

Improve your practice and slow the increasing levels of antimicrobial resistance that already cost around 25,000 deaths across Europe each year.

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Dave Thronton

NHS strikes: goodwill is a two-way processSubscription

By

Dave Thornton explains why the Guild of Healthcare Pharmacists supports the industrial strike action over pay.

The NHS could save huge amounts of money by effective management of medicine and clinical waste

Not all NHS waste is wasteful Subscription

Amidst the drive for efficiency in the NHS, medicines waste must not be oversimplified.

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Career change - moving from the community pharmacy to the hospital pharmacy sector

Changing sector — transferring from community to hospital pharmacySubscription

You have been working in community pharmacy for a few years but are keen to switch to the hospital sector. How likely are you to get the job that you want — and how can you improve your chances of success?

Becoming an independent prescriber

How to become an independent prescriberSubscription

Gaining a non-medical prescribing qualification allows pharmacists to diagnose conditions and prescribe medicines to patients. If you are innovative in your practice and think laterally, many opportunities present themselves, says independent prescriber Anja St Clair Jones.

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Dilip Nathwani, consultant physician in Dundee and chairman of the Scottish Antimicrobial Prescribing Group (SAGP), spoke of the dangers posed by antibiotic resistance were already apparent in other countries

RPS antimicrobial resistance event prompts parliamentary debateSubscription

Politicians in Scotland are set to debate the next steps to take in order to tackle rising antimicrobial resistance.

David Branford, English Pharmacy Board chairman, says government’s decision not to cap pharmacy student numbers could lower the quality of applicants and lead to greater unemployment levels.

Q&A: Failure to cap student numbers risks poorer job prospectsSubscription

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David Branford, English Pharmacy Board chairman, says the government’s decision not to cap pharmacy student numbers could lower the quality of applicants and lead to greater unemployment levels.

Your RPS

The Vale of Leven Hospital inquiry report, chaired by Lord Maclean, criticises NHS Greater Glasgow and Clyde for failure to adopt prudent antibiotic prescribing practices that contributed to the deaths of 34 patients from Clostridium difficule infection

Inquiry criticises NHS Greater Glasgow and Clyde for failure to appoint antimicrobial pharmacistSubscription

Failure to adopt ’prudent’ antibiotic prescribing practices contributed to the deaths of 34 hospital patients from Clostridium difficile infection.

Chief pharmacists warned of the urgent need for succession planning as a large number of NHS pharmacists across the UK responsible for spending some £5bn on hospital medicines are set to retire in the next 5 years, a recent review concluded

Chief pharmacists warned of need for succession planning for procurement rolesSubscription

Succession planning is urgently needed to prepare for the swathe of experienced pharmacists buying medicines for hospitals who will shortly retire, an independent review has warned.

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Lipophilic bisphosphonates, originally used to treat osteoporosis, has demonstrated efficacy against lung adenocarcinoma (pictured).

Lipophilic bisphosphonates used to target lung cancerSubscription

A new generation of lipophilic bisphosphonates has been designed to target cancer, with a zoledronic acid analogue demonstrating efficacy against lung adenocarcinoma.

COX-2 inhibitors linked to worse outcomes after ischaemic stroke (pictured)

Selective COX-2 inhibitors linked to worse outcomes after ischaemic strokeSubscription

New research suggests that selective cyclooxygenase-2 inhibitors herald worse outcomes following ischaemic stroke.

The glioblastoma cells of a patient are used to treat tumour. In picture, MRI scan of a glioblastoma of a brain tumour

Patient’s own glioblastoma cells used to treat tumourSubscription

Hopes for a vaccine to tackle glioblastoma are bolstered by positive results from a phase I trial reported in Cancer Immunology and Immunotherapy.

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Emergence by Renee Rilexie at “Catharsis: a symbiosis of science and art” exhibit

Using art as therapy and visualising science

Benedict Lam looks at an exhibition in London that brings art and science together and spoke to some of the artists to find out their inspiration

Beware the power of knowing your customer

The new profiling tool on the YouGov website is entertaining but has the potential to mislead, writes Emma Page

Googling the bloodstream: how disease might be detected with ingested nanoparticles

Google is developing technology that combines ingested disease-detecting nanoparticles with a wrist sensor.

We must be there for those who are victims of abuse

The legacy of abuse can stay with victims for life, writes Chris Chapman, who heard escaped Westboro Baptist Church member Nate Phelps speak last week.

The afflictions of Henri de Toulouse-Lautrec

Famous as a post-impressionist artist, unfortunate Toulouse-Lautrec was afflicted with pycnodysostosis. David Walsh explains

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The long struggle to ensure prudent use of antibioticsSubscription

Déjà vu was the overwhelming reaction I had to the feature on strategies to reduce the use of antibiotics in animals (The Pharmaceutical Journal 2014;293:517).

The tide is turning in favour of e-cigarettesSubscription

I recently attended the E-Cigarette Summit at the Royal Society in London on 13 November 2014, which aimed to offer the opportunity for debate around the use of e-cigarettes. I am a locum pharmacist and stop smoking adviser, and in my role I come across many patients who are smokers.

Other correspondence

Improving antimicrobial stewardship (video)Video

Anna Cichowska, consultant in public health strategy for NHS England and Mark Gilchrist, consultant pharmacist at Imperial College Healthcare NHS Trust discuss the challenge of antimicrobial resistance and highlight key areas of concern.’

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Special report

Antimicrobial resistance

Last defence dam in antimicrobial resistance

Around 25,000 people die in the European Union each year from infections resistant to antibiotics. Third-generation cephalosporins are often useless against common bacteria like Escherichia coli, and fluoroquinolones are no longer the treatment of choice for gonorrhoea because resistance has become widespread. Here, you can find news stories and articles about the issue.

Read the special report

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Reader's comment

We do view our profession very pessimistically. It is almost assumed by all that the status quo will remain. As clinical services move to the community pharmacy setting and we begin to manage patients there, the demand for skilled prescribing pharmacists will increase.

Johnathan Laird Pharmacy workforce remains a dilemma