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Blood clot illustration

Apixaban more effective than warfarin regardless of polypharmacySubscription

The oral anticoagulant apixaban is consistently more effective than warfarin for patients with atrial fibrillation regardless of the number of other drugs they take, a study has found. 

Close up of a melanoma

Risk of melanoma in men taking erectile dysfunction drugs driven by sun exposure Subscription

Study of men taking phosphodiesterase 5 inhibitors found an increased risk of melanoma driven by sun exposure.

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Drone carrying abortion pills

Drone flies abortion pills to Northern Ireland to highlight its abortion laws

Source: Marc Godefroy Two women met the drone where it landed near Warrenpoint in Northern Ireland and and took the mifepristone and misoprostol pills that it was carrying as part of the pro-choice demonstration

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Owen Wood works as a ‘flying’ pharmacist for Médicins San Frontières (MSF)

What I do as a flying pharmacist in Democratic Republic of CongoSubscription

As a pharmacist working for an international charity, Owen Wood shares his knowledge of mass vaccination and medicines procurement.

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Anchin Pavilion (Florida, US) residents Helen Waldman and Jerry Osterweild experience Kobernick-Anchin-Benderson’s Multisensory and Reflections Program.

Dementia care: an overview of available non-pharmacological therapiesSubscription

A summary of non-pharmacological therapies for patients with dementia that may be used alongside licensed medicines.

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3D MRI scan of a breast with breast cancer

Improving long-term adjuvant anti-oestrogenic therapy for breast cancerSubscription

By ,

Abstract Long-term (five years) adjuvant tamoxifen treatment for oestrogen receptor-positive, or ER-positive, breast cancer post-surgery is recognised as a major advance in healthcare. Clinical trials comparing standard and extended tamoxifen therapy found a major decrease in mortality occurred in the ten years following a decade of adjuvant therapy. Studies in premenopausal breast cancer patients showed that ovarian function suppression (OFS) plus an aromatase ...

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Why we should be wary about plastic food containers

A contributing factor to the rise of premature births and the early onset of puberty may be the use of the chemical BPA in plastic products.

April 2016: Who read what on pharmaceutical-journal.com

Find out what other readers found useful in April 2016 and discover the most popular articles and sections on pharmaceutical-journal.com

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Balance with a single person on one side bringing up an entire group of people on the other, representing a lack of democracy

Do not blame RPS members for not voting in the board elections — give them something to vote forSubscription

The low number of members who voted in the RPS pharmacy board elections does not equate to apathy or despondency about pharmacy as a whole. 

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Timeline and infographic showing the development and safety of proton pump inhibitors

The development and safety of proton pump inhibitorsSubscription

Since the discovery of omeprazole in 1979, dispensing of proton pump inhibitors (PPIs) in England has increased more than 100-fold, and several products are now available without prescription. Although PPIs are effective and generally well tolerated, observational studies suggest an association with several adverse effects. Further trials are needed to establish causal relationships. 

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Cover of ‘Extemporaneous formulations for pediatric, geriatric and special needs patients, 3rd edition’

Extemporaneous formulations reference guideSubscription

‘Extemporaneous formulations for pediatric, geriatric and special needs patients, 3rd edition’, by Rita K Jew, Winson Soo-Hoo, Sarah C Erush and Elham Amiri.

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Ash Soni, president of the Royal Pharmaceutical Society

Ash Soni loses RPS presidency

Following a vote by the Royal Pharmaceutical Society (RPS) English Pharmacy Board on 22 June 2015 to elect Assembly members for 2016/2017, RPS president Ash Soni has lost his seat on the Assembly, meaning he will no longer be president from 19 July 2016.

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Illustration of chronic obstructive pulmonary disease (COPD)

Chronic obstructive pulmonary disease: clinical phenotypes and implications for managementSubscription

Phenotyping patients with chronic obsructive pulmonary disease allows their separation into distinct categories that differentiate their prognosis and response to treatment, producing clinically meaningful outcomes.

Computer illustration of a low-density lipoprotein (LDL) molecule (round) bound to an LDL receptor (LDLR) protein, with a molecule of the enzyme proprotein convertase subtilisin/kexin type 9 (PCSK9, blue) bound to a PCSK9 inhibitor antibody (orange)

Non-statin drugs for the management of dyslipidaemia in adultsSubscription

The role of non-statin drugs, including ezetimibe, fibrates, bile acid binders, nicotinic acid derivatives, omega-3 fatty acid supplements and PCSK9 inhibitors, for the management of dyslipidaemia in adults.

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Special report

Summary of the new pharmacy registration assessment in Great Britain

This year’s pharmacy registration assessment will take place on 30 June 2016. UK pharmacy regulator, the General Pharmaceutical Council, has changed the format of the assessment for candidates sitting the papers from 2016. These articles summarise the changes and explain what candidates can expect. This page also contains information about registration assessments in previous years and various opinions on their value, content and format.

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Michelle Sullivan, pharmacy technician at Barts Health NHS Trust in London, speaks with one of the hospital staff

The rise of the pharmacy technician: the next stepsSubscription

Pharmacy technicians are taking on more responsibilities to free pharmacists to carry out clinical services, but the role is being interpreted differently across pharmacy settings and there is no clear definition of what the role should entail.

X-ray of lungs with cystic fibrosis

Developing gene therapy to treat cystic fibrosis: challenges and successesSubscription

More than 25 years after the gene for cystic fibrosis was discovered, there are signs that correcting this genetic deficit could soon be possible.

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The Pharmaceutical Journal's panel discussion: Medicines, innovation and the value of medicine

The Pharmaceutical Journal's panel discussion: Medicines, innovation and the value of medicineSubscription

Key opinion leaders were brought together to debate the controversial topic of highly priced medicines at The Pharmaceutical Journal’s panel discussion on 14 September 2015 at the Royal Pharmaceutical Society’s annual conference in Birmingham.

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Statin myopathy stain showing muscle fibres in varying stages of necrosis, phagocytes and regeneration

Statins: general safety profile and association with myopathySubscription

By ,

Abstract Statin therapy has demonstrated remarkable efficacy in reducing mortalities associated with cardiovascular diseases through preventing myocardial infarction and ischaemic stroke. Despite the proven benefits of statins in this context, there are growing concerns among patients and physicians on the safety of short-term and long-term use and their adverse effects, especially muscle toxicity, resulting in non-adherence and withdrawal of the treatment. ...

Hospital staff at Airedale NHS Foundation Trust use the new electronic prescribing system on the drugs round

Impact of electronic prescribing on patient safety in hospitals: implications for the UKSubscription

By , , , ,

Abstract NHS hospitals in England are expected to be paperless by 2020, as set out in a comprehensive framework published by the National Information Board. The use of hospital electronic prescribing (EP) systems is therefore likely to increase rapidly in the near future. The aim of this review is to summarise the available evidence of the impact of inpatient EP on patient safety, with a focus on implications for the UK. MEDLINE and EMBASE were searched to ...

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A reference you need

British National Formulary, 71st edition

Up-to-date, practical guidance on prescribing, dispensing, administering medicines and current best practice relating to the uses of medicines, as well as legal and professional guidelines.

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