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Close-up of pills on an elderly person's hands

Beta-blockers risk functional decline in some older patientsSubscription

Nursing home residents with pre-existing cognitive or functional impairments were at a higher risk of functional decline after taking beta-blockers following acute myocardial infarction, study shows.

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Shortening antibiotic treatment worsens outcomes in children with ear infectionSubscription

Researchers found that standard-duration antibiotic treatment for acute otitis media works better than shorter treatments.

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Non-aspirin NSAIDs outperform aspirin for colorectal cancer preventionSubscription

Non-aspirin NSAIDs offer protection against colorectal cancer but carry a high risk of adverse events.

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Ocrelizumab cuts relapse rates and disability progression in MSSubscription

Researchers found ocrelizumab to be more effective than interferon beta-1a for treating relapsing MS

Chemotherapy drugs on tray

Modelling approach could optimise drug combination choiceSubscription

Researchers used polynomial modelling to simulate complex drug-dose effects and found that they could accurately predict the dose-effect function of drug combinations.

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Antibodies from Zika patient protect mice against diseaseSubscription

Attempts to isolate human monoclonal antibodies (mAbs) against Zika virus have led to broadly neutralising antibodies that also show activity against Dengue virus.

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Daily Vaseline use could be cost-effective way to prevent eczemaSubscription

Recent attention has turned to ways to prevent atopic dermatitis, which is associated with significant expenditure as well as comorbidities, from developing in children.

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Low vitamin D levels linked to headaches in menSubscription

Some evidence has linked headache prevalence to increasing latitude, indicating a possible role for vitamin D exposure. But there are limited data to support this hypothesis.

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Women may mistake menopause symptoms for side effects of tamoxifenSubscription

The International Breast Cancer Intervention Study found that tamoxifen reduces the risk of breast cancer by over 30% in high-risk women, but a third of participants discontinued treatment before the recommended five years were up.

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SSRI could relieve aromatase inhibitor side effectsSubscription

Adherence to aromatase inhibitor therapy by women with hormone receptor-positive breast cancer is often poor because of the occurrence of musculoskeletal side effects.

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IUD and subdermal contraceptives minimise thromboembolism riskSubscription

A US study considers the safety of hormonal contraception with regard to thromoboembolic events for women with diabetes.

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Flu vaccination during late pregnancy not associated with autism riskSubscription

Research indicates maternal infections and fever during pregnancy might be associated with an increased risk of autism spectrum disorder (ASD).

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Increased duration of OTC painkiller use increases risk of hearing loss

Researchers say their findings suggest that a “significant proportion” of hearing loss is owed to paracetamol or NSAID-related ototoxicity.

Child's ear

Data lacking on childhood hearing loss following platinum-based cancer therapySubscription

Inconclusive data review leads researchers to advise clinicians to continue warning patients about the risk of hearing loss resulting from platinum-based cancer treatment.

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Targeted treatment shows promise for severe spinal muscular atrophySubscription

Antisense drug nusinersen was well tolerated in trial of 20 babies with SMA, with majority showing improved muscle skills and function after treatment.

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Ambulatory blood pressure higher than clinic BP, study showsSubscription

Researchers say 24-hour ambulatory BP monitoring could benefit people with prehypertension following trial of 888 people. 

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Pharmacist review boosts detection of inappropriate prescribingSubscription

Inclusion of a pharmacist in the multidisciplinary team could detect more cases of potentially inappropriate prescribing, study results suggest.

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Vitamin D levels at birth linked to MS risk in later lifeSubscription

Researchers found an inverse relationship between vitamin D levels in dried blood spots up to seven days after birth and the risk of developing MS in later life. 

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