Researchers found small decreases in blood pressure and heart rate in patients treated with guanfacine, and say further clinical testing is needed.
Opioid-receptor agonist demonstrated similar level of pain relief to fentanyl but without typical side effects associated with opioids.
Researchers found that smokers who relapsed while trying to quit had a reduced functional connectivity between brain regions involved in inhibitory control, compared to those who remained abstinent.
Adding pravastatin to platinum-based chemotherapy offered no benefit to survival compared with placebo, researchers report.
Scientists find a new chemical probe that is a potent inhibitor of human cancer cell proliferation in vitro, with potential applications against many cancers.
Researchers say their study using a mouse model of chronic social defeat stress could be applied to identify novel drug targets for depression therapies.
Animal research suggests that frequent consumption of aspirin could contribute to S. aureus infection.
Researchers found that a single dose of their mRNA-based Zika vaccine could protect mice for up to five months.
University of California researchers found that e-cigarette users were more likely to show increased cardiac sympathetic activity and higher levels of oxidative stress.
Study results show that 22% of patients taking placebo with naproxen for back pain reported moderate to severe pain, compared with 32% of patients taking diazepam with naproxen.
Pharmacist prescribers are as competent as medical students when it comes to safe prescribing, pilot study shows.
Restricting the prescribing of fluoroquinolone seems to explain the reduced rates of C. difficile infections in England over the past decade, national study shows.
Pharmacist-led interventions and patient education are better at improving adherence to lipid-lowering drugs than other types of intervention, such as electronic or telephone reminders, study results show.
Researchers injected 16 adult male monkeys with Vasalgel; their mates did not conceive for the duration of the two-year study.
Nursing home residents with pre-existing cognitive or functional impairments were at a higher risk of functional decline after taking beta-blockers following acute myocardial infarction, study shows.
Researchers found that standard-duration antibiotic treatment for acute otitis media works better than shorter treatments.
Non-aspirin NSAIDs offer protection against colorectal cancer but carry a high risk of adverse events.
Researchers found ocrelizumab to be more effective than interferon beta-1a for treating relapsing MS
Researchers used polynomial modelling to simulate complex drug-dose effects and found that they could accurately predict the dose-effect function of drug combinations.
Attempts to isolate human monoclonal antibodies (mAbs) against Zika virus have led to broadly neutralising antibodies that also show activity against Dengue virus.