Nursing home residents with pre-existing cognitive or functional impairments were at a higher risk of functional decline after taking beta-blockers following acute myocardial infarction, study shows.
Researchers found that standard-duration antibiotic treatment for acute otitis media works better than shorter treatments.
Non-aspirin NSAIDs offer protection against colorectal cancer but carry a high risk of adverse events.
Researchers found ocrelizumab to be more effective than interferon beta-1a for treating relapsing MS
Researchers used polynomial modelling to simulate complex drug-dose effects and found that they could accurately predict the dose-effect function of drug combinations.
Attempts to isolate human monoclonal antibodies (mAbs) against Zika virus have led to broadly neutralising antibodies that also show activity against Dengue virus.
Recent attention has turned to ways to prevent atopic dermatitis, which is associated with significant expenditure as well as comorbidities, from developing in children.
Low vitamin D levels linked to headaches in menSubscription
Some evidence has linked headache prevalence to increasing latitude, indicating a possible role for vitamin D exposure. But there are limited data to support this hypothesis.
The International Breast Cancer Intervention Study found that tamoxifen reduces the risk of breast cancer by over 30% in high-risk women, but a third of participants discontinued treatment before the recommended five years were up.
Adherence to aromatase inhibitor therapy by women with hormone receptor-positive breast cancer is often poor because of the occurrence of musculoskeletal side effects.
A US study considers the safety of hormonal contraception with regard to thromoboembolic events for women with diabetes.
Research indicates maternal infections and fever during pregnancy might be associated with an increased risk of autism spectrum disorder (ASD).
Researchers say their findings suggest that a “significant proportion” of hearing loss is owed to paracetamol or NSAID-related ototoxicity.
Inconclusive data review leads researchers to advise clinicians to continue warning patients about the risk of hearing loss resulting from platinum-based cancer treatment.
Antisense drug nusinersen was well tolerated in trial of 20 babies with SMA, with majority showing improved muscle skills and function after treatment.
Researchers say 24-hour ambulatory BP monitoring could benefit people with prehypertension following trial of 888 people.
Inclusion of a pharmacist in the multidisciplinary team could detect more cases of potentially inappropriate prescribing, study results suggest.
Researchers found an inverse relationship between vitamin D levels in dried blood spots up to seven days after birth and the risk of developing MS in later life.