Researchers say their findings suggest that a “significant proportion” of hearing loss is owed to paracetamol or NSAID-related ototoxicity.
Inconclusive data review leads researchers to advise clinicians to continue warning patients about the risk of hearing loss resulting from platinum-based cancer treatment.
Antisense drug nusinersen was well tolerated in trial of 20 babies with SMA, with majority showing improved muscle skills and function after treatment.
Researchers say 24-hour ambulatory BP monitoring could benefit people with prehypertension following trial of 888 people.
Inclusion of a pharmacist in the multidisciplinary team could detect more cases of potentially inappropriate prescribing, study results suggest.
Researchers found an inverse relationship between vitamin D levels in dried blood spots up to seven days after birth and the risk of developing MS in later life.
Data from 244,679 patients that had undergone endoscopy show that stroke incidence was 19% higher in patients who filed a prescription for a PPI compared with those with no PPI exposure
Researchers say perindopril or bisoprolol may increase patients’ chance of receiving full course of trastuzumab, which is often stopped at the first sign of heart failure.
Patients with no CYP2C19 enzyme expression in the womb had a lower prevalence of depressive disorder compared with those who expressed the enzyme, researchers found.
PCSK9 inhibitor shows plaque reduction benefitSubscription
Patients with coronary disease who were treated with evolocumab achieved lower LDL-C levels and greater plaque reduction, trial results show.
Using Bdellovibrio to control Shigella infection in zebrafish larvae, researchers say this type of living antibiotic could hold potential for tackling antimicrobial resistance.
Statins were associated with a 36% lower risk of heart attack and 29% lower risk of stroke compared with placebo in a review of data from more than 70,000 patients.
Combining HIV vaccination with immune stimulation delayed viral rebound in monkeys with simian immunotherapy virus.
Dextrose gel prevents hypoglycaemia in newbornsSubscription
Study results show that newborns given dextrose gel were less likely to develop hypoglycaemia, but researchers say more research is required in babies from other risk groups.
Study results show that children born to mothers who took SSRIs during pregnancy were more than a third more likely to have speech/language disorders.
Pharmacists in New Zealand who are allowed to give women with uncomplicated cystitis a three-day supply of trimethoprim say patients appreciate the improved access to treatment.
While persistence rates favoured patients taking a fixed dose combination of a statin and ezetimibe, it made no difference to adherence, researchers found.
A vaccine using siderophores reduced bacterial burden in the urine and kidneys of mice, researchers report.
Rates of post-surgical infections did not increase for patients taking disease-modifying anti-rheumatic drugs and biologics, researchers discover.
Gout treatment does not raise CKD riskSubscription
Study shows serum urate levels can be lowered using allopuruinol in gout without risk to kidneys.