Cookie policy: This site uses cookies (small files stored on your computer) to simplify and improve your experience of this website. Cookies are small text files stored on the device you are using to access this website. For more information please take a look at our terms and conditions. Some parts of the site may not work properly if you choose not to accept cookies.

Join

Subscribe or Register

Existing user? Login

NSAIDs

Diazepam should not be added to NSAIDs for acute lower back pain, researchers say

Study results show that 22% of patients taking placebo with naproxen for back pain reported moderate to severe pain, compared with 32% of patients taking diazepam with naproxen.

Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended for patients with acute back pain. In emergency settings, benzodiazepines, such as diazepam, are often concomitantly prescribed, but there is no clear evidence to support this practice.

Reporting in Annals of Emergency Medicine[1] (online, 7 February 2017), researchers studied 112 patients who attended an emergency department for acute lower back pain and were randomly assigned to receive the NSAID naproxen plus placebo, or naproxen plus diazepam for one week.

One week following discharge, scores on the Roland-Morris Disability Questionnaire had improved by the same amount — 11 points — in both groups of patients. The researchers also found that the percentage of patients reporting moderate or severe pain was 22% in those assigned to placebo compared with 32% in the diazepam group.

The team concludes that diazepam should not routinely be added to NSAIDs for the treatment of acute lower back pain. 

Citation: Clinical Pharmacist DOI: 10.1211/CP.2017.20202403

Have your say

For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.

Recommended from Pharmaceutical Press

  • Integrated Pharmacy Case Studies

    Integrated Pharmacy Case Studies

    Over 90 case studies based on real life patient-care scenarios. Each case includes learning outcomes and references.

    £42.00Buy now
  • Drugs in Use

    Drugs in Use

    Optimise drug therapy for your patients. These case studies help you bridge the gap between theoretical medicines knowledge and practical applications.

    £42.00Buy now
  • Application and Review of Pediatric Pharmacotherapy

    Application and Review of Pediatric Pharmacotherapy

    Increase your understanding of pharmacotherapy prescribed to pediatric patients with these realistic case studies.

    £32.00Buy now
  • Pharmacy Case Studies

    Pharmacy Case Studies

    Understand the application of therapeutics in clinical practice with Pharmacy Case Studies. This book helps you to demonstrate the knowledge gained during your studies.

    £32.00Buy now
  • Disease Management

    Disease Management

    Disease Management covers the diseases commonly encountered in primary care by system, with common therapeutic issues. Includes case studies and self-assessment sections.

    £52.00Buy now
  • Introduction to Pharmaceutical Calculations

    Introduction to Pharmaceutical Calculations

    Introduction to Pharmaceutical Calculations is an essential study aid for pharmacy students. The book contains worked examples and sample questions and answers.

    £32.00Buy now

Search an extensive range of the world’s most trusted resources

Powered by MedicinesComplete
  • Print
  • Share
  • Comment
  • Save
  • Print Friendly Version of this pagePrint Get a PDF version of this webpagePDF

Supplementary images

  • Diazepam tablets

Newsletter Sign-up

Want to keep up with the latest news, comment and CPD articles in pharmacy and science? Subscribe to our free alerts.