Cookie policy: This site uses cookies (small files stored on your computer) to simplify and improve your experience of this website. Cookies are small text files stored on the device you are using to access this website. For more information please take a look at our terms and conditions. Some parts of the site may not work properly if you choose not to accept cookies.


Subscribe or Register

Existing user? Login

Erectile dysfunction

Erectile dysfunction drugs linked to decreased mortality after heart attack

Users of phosphodiesterase-5 inhibitors were found to have lower risk of death or rehospitalisation after heart attack.

Erectile dysfunction is associated with an increased risk of cardiovascular disease, but it is unknown what effect the condition has on outcomes following a heart attack.

To find out, researchers studied data on 43,145 men in Sweden aged under 80 years who were hospitalised for a first myocardial infarction.

Over a mean follow-up of 6.2 years, they found that the 7% of men who filed a prescription for an erectile dysfunction medication had a 33% reduced risk of mortality and 40% reduced risk of hospitalisation for heart failure. Further analysis showed that this reduction in mortality risk was only observed in users of phosphodiesterase-5 (PDE5) inhibitors and not alprostadil users.

Publishing their report in Heart[1] (online, 9 March 2017), the researchers say the findings should reassure doctors that they can prescribe PDE5 inhibitors to men after a heart attack, provided there are no contraindications.

Citation: Clinical Pharmacist DOI: 10.1211/CP.2017.20202560

Have your say

For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.

Recommended from Pharmaceutical Press

Search an extensive range of the world’s most trusted resources

Powered by MedicinesComplete
  • Print
  • Share
  • Comment
  • Save
  • Print Friendly Version of this pagePrint Get a PDF version of this webpagePDF

Supplementary images

  • Molecular structure of PDE5 inhibitor

Newsletter Sign-up

Want to keep up with the latest news, comment and CPD articles in pharmacy and science? Subscribe to our free alerts.