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In this issue

Insight

Medicines-related hospital readmissions are a huge cost to the national health system, but there are ways to reduce this cost

Reducing preventable hospital readmissions: a way forward Subscription

By ,

Medicines-related hospital readmissions are a huge cost to the NHS, but there are ways to reduce this.

Correspondence

Electronic discharge advice letters for community pharmacistsSubscription

By

The 2009 Care Quality Commission annual report revealed limitations in the transfer of information between sectors. When a patient is discharged from hospital with a change of medicine, completeness and timeliness of the information were highlighted as issues. In Wales, to improve communication between primary and secondary care and to aid the seamless transition of care for the patient, the discharge medicines review (DMR) service was established in autumn 2011.

Reducing hospital admissions of frail elderly patientsSubscription

By Karen Varisco

The proactive care service in Coastal West Sussex (CWS), which was shortlisted for the HSJ Awards in 2015, provides medicines optimisation for frail elderly patients, reduces the risk of hospital admissions and made estimated savings of more than £600,000 in one year.

Pharmacist interventions on a cardiothoracic critical care unitSubscription

By

During ward rounds in hospitals, pharmacists often make interventions and recommendations that help optimise the care of patients. At Basildon and Thurrock University Hospitals NHS Foundation Trust, we carried out a service evaluation to analyse pharmacist interventions on a 16-bed cardiothoracic critical care unit. We wanted to find out the frequency and types of interventions made by the ward pharmacist; evaluate the effect of pharmacist attendance to ward rounds on the total number ...

Absolute levels of risk are needed to make informed decisions for patientsSubscription

By

Renal adverse effects of proton pump inhibitors (PPIs) were described in your research briefing ‘Proton pump inhibitors linked with chronic kidney disease’ (Clinical Pharmacist

Research briefing

Scientists have successfully restored function of the mutated dystrophin gene in mice by packaging the CRISPR/Cas9 gene-editing system (pictured) into a virus and injecting it into the muscle or bloodstream

Gene editing used to treat muscular dystrophy in miceSubscription

5 JAN 2016

CRISPR/Cas9 system injected into muscle or bloodstream restored function of dystrophin gene, marking an important step in gene therapy research.

New anti-platelet drug set for phase II study after success in patients with coronary heart disease. Pictured, a blood clot in coronary artery.

Novel anti-platelet therapy shows promise in first human trialsSubscription

24 DEC 2015

New anti-platelet drug set for phase II study after success in patients with coronary heart disease.

Surgery may not be necessary for children with uncomplicated appendicitis. In the picture, a doctor examining a boy's abdomen.

Antibiotic management is effective for uncomplicated appendicitisSubscription

24 DEC 2015

Surgery may not be necessary for children with uncomplicated appendicitis, study shows.

Danish study shows medication errors on hospital ward fell by 57% following introduction of automated system. In the image, nurse prepares medication for patient

Hospital medication errors halved by automated system Subscription

16 DEC 2015

Danish study shows medication errors on hospital ward fell by 57% following introduction of automated system.

CPD article

When insulin fails to bind and Glut-4 is not activated, glucose cannot enter the cell (left) and returns to the bloodstream, elevating the blood-sugar level

Insulin initiation in patients with diabetesSubscription

By

How to select and start insulin in a patient with diabetes mellitus.

Chronic Kidney Disease - Mineral and Bone Disorder (CKD-MBD) is used to describe the pathophysiological changes that occur in the vascular and skeletal system in CKD and was previous called renal bone disease (light micrograph pictured)

Chronic Kidney Disease – Mineral and Bone Disorder: pathophysiology and treatmentSubscription

By ,

How the pathophysiological mechanisms behind development of Chronic Kidney Disease - Mineral and Bone Disorder can be managed, using appropriate therapeutic interventions to prevent complications.

Review

The safety of antiepileptic drug use in pregnancy involves: the pregnant woman in her own right; the foetus while in her womb; and during its subsequent extra-uterine existence as a neonate and infant. Pregnant woman during an ultrasound scan pictured

Antiepileptic drug safety in pregnancy: possible dangers for the pregnant woman and her foetusSubscription

By

In addition to the safety issues that apply whenever antiepileptic drugs are taken by patients, additional safety-related matters arise in pregnant women. These may involve the women themselves or their foetuses, and apply both during, and for a time after, pregnancy. During pregnancy, the safety of women with epilepsy may be endangered by loss of seizure control caused by increased antiepileptic drug clearances not being compensated for by appropriate adjustments of drug dosages. ...

Clinical Pharmacist

CP January 2016, Vol 8, No 1

Cover Story:

The use of antiepileptic drugs during pregnancy.

Read more…

Clinical Pharmacist

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Clinical Pharmacist is a monthly, peer-reviewed journal that provides authoritative resources on the clinical management of disease in relation to medicines and up-to-date information about advances in pharmacy and drug development. Clinical Pharmacist publishes Review articles, Perspectives, evidence-based CPD articles and Practice Reports on topics from drug discovery to clinical pharmacology and pharmacy.

The international audience of Pharmaceutical Journal Publications consists of pharmacists, pharmaceutical scientists and healthcare professionals. The journal is available to 44,000 members of the Royal Pharmaceutical Society, as well as non-member individual subscribers and subscribing institutions.