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In this issue

Insight

Illustration of asthma, inhaler, lungs and pills

Dangers with inappropriate use of long-acting beta agonists Subscription

By , ,

Caution is required when prescribing or dispensing long-acting beta agonists to manage airways diseases, such as asthma.

Perspective article

Scanning electron micrograph (SEM) of a lymphocyte with HIV cluster

Pre-exposure prophylaxis should be a key component of a comprehensive HIV prevention package fully funded on the NHSSubscription

By

Abstract Pre-exposure prophylaxis (PrEP) is the medication taken by HIV-negative individuals to reduce their risk of contracting HIV infection. The large evidence base for the use of PrEP has been reviewed and recommended by the World Health Organization (WHO), a specialised agency of the United Nations that is concerned with international public health, the Joint United Nations Programme on HIV and AIDS (UNAIDS) and the National Institute for Health and Care ...

Review

Geneticist at the French National Institute for Health and Medical Research (Inserm) researches genetic diseases like cystic fibrosis

Conventional therapies and emergent precision medicines for cystic fibrosis: challenges and opportunitiesSubscription

By

Abstract Around 27 years ago, the discovery of the cystic fibrosis transmembrane conductance regulator (CFTR) gene – responsible for causing cystic fibrosis (CF) – marked a significant moment in the history of the condition. Despite the early promise of this target for gene therapy, a universally successful treatment has proven elusive in the ensuing years. While clinical trials involving gene therapy continue to make progress, the ‘magic bullet’ remains some ...

Short communications

Child obesity rates continue to grow in England — we need action nowSubscription

By

In October 2016, NHS Digital released the latest set of figures from the National Child Measurement Programme (NCMP). Another set of childhood obesity statistics and another bleak picture. Year on year, we are faced with sobering figures that reveal an increasingly worrying trend: the number of obese and overweight children in the UK is not falling and is, in fact, rising.

Promoting self care to reduce unnecessary GP visitsSubscription

By

Healthcare is changing dramatically and so are the needs of our patients. As such, GPs and our teams are changing the ways in which we are working, but we also need our patients to play their part.

We need safe and better labelled vitamin D products on the marketSubscription

By

Recommended vitamin D intakes for all of us living in the UK have changed following the publication of a report from the Scientific Advisory Committee on Nutrition (SACN) on 22 July 2016. New guidelines were required because of the persisting problem relating to vitamin D deficiency: cases of rickets and seizures continue to be

Researchers wanted Subscription

By

We are looking for researchers who are working on medicines supply and shortages of medicines to join a network of researchers in the UK and other European countries so that they can meet and share their knowledge. Financial support is available for travel and accommodation to workshops and conferences and grants are available towards attendance at training schools and short-term scientific missions (exchange visits of a few days). In particular, we are looking for “early career investigators”,

Spotting the signs of oral mouth cancer in pharmacySubscription

By

In the UK, mouth cancer cases have increased by 39% in the past decade and by 92% since the 1970s. In fact, it is one of a small number of cancers that is continuing to see cases increase. Alongside this, survival rates have not improved in the same period and, sadly, more than 2,000 lives are lost to the disease every year. This is twice as many as cervical and testicular cancers combined and much of this can be attributed to late diagnosis.

Parkinson’s disease-specific medicines use reviewSubscription

By

Members of Royal Pharmaceutical Society’s London North West Local Practice Forum (LNW LPF) are working with charity Parkinson’s UK to develop a new service for patients with Parkinson’s disease (PD). The overall aim is to develop a PD-specific medicines use review by designing and trialling it in an initial and follow-up trial.

How to spot signs of postnatal depression in the pharmacySubscription

By

In light of singer Adele’s recent admission in an interview that she has suffered from postnatal depression (PND), I would like to alert readers how they can spot the signs and help those who might be affected in their day-to-day work in the pharmacy.

Research briefing

Molecular structure of trimethoprim

New Zealand pharmacists support OTC trimethoprim prescribingSubscription

2 DEC 2016

Pharmacists in New Zealand who are allowed to give women with uncomplicated cystitis a three-day supply of trimethoprim say patients appreciate the improved access to treatment.

Open pill bottle with different medicines spilling out

Fixed dose combination products have little impact on medicines adherenceSubscription

1 DEC 2016

While persistence rates favoured patients taking a fixed dose combination of a statin and ezetimibe, it made no difference to adherence, researchers found.

Micrograph of Escherichia coli

Small molecule vaccine protects against UTI in miceSubscription

1 DEC 2016

A vaccine using siderophores reduced bacterial burden in the urine and kidneys of mice, researchers report.

X-ray of arthritic hands

DMARDs do not increase post-surgical infection riskSubscription

30 NOV 2016

Rates of post-surgical infections did not increase for patients taking disease-modifying anti-rheumatic drugs and biologics, researchers discover.

Clinical Pharmacist

CP December 2016, Vol 8, No 12

Cover Story:

PrEP should be fully funded by the NHS to prevent HIV

Read more…

Clinical Pharmacist

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Clinical Pharmacist is a monthly, peer-reviewed journal that provides authoritative resources on the clinical management of disease in relation to medicines and up-to-date information about advances in pharmacy and drug development. Clinical Pharmacist publishes Review articles, Perspectives, evidence-based CPD articles and Research articles on topics from drug discovery to clinical pharmacology and pharmacy.

The international audience of Pharmaceutical Journal Publications consists of pharmacists, pharmaceutical scientists and healthcare professionals. The journal is available to 44,000 members of the Royal Pharmaceutical Society, as well as non-member individual subscribers and subscribing institutions.