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In this issue

Insight

Illustration of pills "falling" into an open mouth representing polypharmacy

How polypharmacy has become a medical burden worldwideSubscription

By , ,

More patients than ever are taking a multitude of medicines and supplements, but this can cause more harm than good.

Correspondence

Reducing medication discrepancies in elderly patientsSubscription

By ,

Older patients are more susceptible to harm from polypharmacy and transfer between care settings can result in medication discrepancies. To address this issue Birmingham South Central Clinical Commissioning Group (CCG), in partnership with NHS Midlands and Lancashire Commissioning Support Unit, conducted a pilot project, where prescribing support via a pharmacist and pharmacy technician were offered to GPs through conducting post-discharge medication reviews in patients who were aged ...

No guarantee of quality with unlicensed vitamin D productsSubscription

By

Colin Michie’s article on the risks of vitamin D self supplementation makes many useful points, including the risks associated with excess vitamin D  (Clinical Pharmacist, 2016;8:131). But there is one major issue that was not highlighted: the vast majority of vitamin D products sold through pharmacies and elsewhere ...

A downside to electronic prescribingSubscription

By Alan G. Paul

I write regarding your excellent review in the May edition of Clinical Pharmacist (2016;8:144).

We need more investment in diagnostics for asthmaSubscription

By

Recent headlines in national media have declared that asthma is ‘overdiagnosed and trivialised’. But as I am sure your readers know, these news stories are masking a deeper issue: there is no simple diagnostic test for asthma. It is shocking that in the 21st century we still do not have a simple test to be able to tell if someone has asthma, a condition so ...

We need to reduce dental consultations in GP surgeries and pharmaciesSubscription

By ,

The paper by Cope et al. (Dental consultations in UK general practice and antibiotic prescribing rates: a retrospective cohort study, Br J Gen Pract 2016) is a timely update on dental ...

Research briefing

MRI scan of a brain with stroke

Early aspirin use after transient ischaemic attack cuts severe stroke risk by 90%Subscription

1 JUN 2016

Large analysis of data shows taking aspirin within two weeks of transient ischaemic attack or stroke cuts risk of secondary stroke by over 90%.

Doctor holds the umbilical cord of a newborn baby

Umbilical cords longer in babies exposed to SSRIsSubscription

27 MAY 2016

Data show babies born to women who used SSRIs also had lower Apgar scores and were more likely to be admitted to neonatal intensive care.

Fluorescent micrograph of endothelial cells

Study shows how proton pump inhibitors damage blood vessel cellsSubscription

25 MAY 2016

New research into harmful effects of PPIs suggests that the drugs impair vascular cells.

Crossed polars of ketamine, crystallised from an aqueous solution

Ketamine metabolite relieves depression with fewer side effectsSubscription

25 MAY 2016

Study findings could inform the development of more effective and safe treatments for depression.

CPD article

Illustration of chronic obstructive pulmonary disease (COPD)

Chronic obstructive pulmonary disease: clinical phenotypes and implications for managementSubscription

By ,

Phenotyping patients with chronic obsructive pulmonary disease allows their separation into distinct categories that differentiate their prognosis and response to treatment, producing clinically meaningful outcomes.

Perspective article

3D MRI scan of a breast with breast cancer

Improving long-term adjuvant anti-oestrogenic therapy for breast cancerSubscription

By ,

Abstract Long-term (five years) adjuvant tamoxifen treatment for oestrogen receptor-positive, or ER-positive, breast cancer post-surgery is recognised as a major advance in healthcare. Clinical trials comparing standard and extended tamoxifen therapy found a major decrease in mortality occurred in the ten years following a decade of adjuvant therapy. Studies in premenopausal breast cancer patients showed that ovarian function suppression (OFS) plus an aromatase ...

Clinical Pharmacist

CP May 2016, Vol 8, No 6

Cover Story:

Long-term anti-hormone therapy for breast cancer

Read more…

Clinical Pharmacist

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Clinical Pharmacist is a monthly, peer-reviewed journal that provides authoritative resources on the clinical management of disease in relation to medicines and up-to-date information about advances in pharmacy and drug development. Clinical Pharmacist publishes Review articles, Perspectives, evidence-based CPD articles and Practice Reports on topics from drug discovery to clinical pharmacology and pharmacy.

The international audience of Pharmaceutical Journal Publications consists of pharmacists, pharmaceutical scientists and healthcare professionals. The journal is available to 44,000 members of the Royal Pharmaceutical Society, as well as non-member individual subscribers and subscribing institutions.