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In this issue

Insight

Identical vials held by gloved hands

Why biosimilars should be interchangeable with biologicsSubscription

By

Research suggests no substantive outcome differences between the use of originator biologics and their biosimilar counterparts Source: Shutterstock.com

CPD article

coloured scanning electron micrograph (SEM) of bacterial blood infection (sepsis) caused by a rod shaped bacterium (blue)

Sepsis: an update on identification and management Subscription

By , ,

All healthcare professionals, including pharmacists, should be aware of the clinical features and management of sepsis. This article summarises the recent changes in the definition of sepsis in adults, as well as its management.

Review

Image 1 shows a normal spine and image 2 shows a spine affected by spondylitis

TNFα-inhibitors for ankylosing spondylitis and non-radiographic axial spondyloarthritisSubscription

By , , , , , , , , ,

Abstract Spondyloarthropathy refers to a group of articular inflammatory diseases that share common genetic, clinical and radiological features in addition to their association with human leucocyte antigen (HLA)-B27 antigen. The aim of therapeutic management of patients with spondyloarthritis is to improve quality of life, control the symptoms of articular inflammation, prevent the structural damage of joints, and preserve the functional abilities, autonomy and social participation ...

Close up of a woman's hand holding hormone replacement therapy (HRT) pills

Establishing the risk related to hormone replacement therapy and cardiovascular disease in womenSubscription

By ,

Abstract Hormone replacement therapy (HRT) has a profound impact on the cardiovascular system in postmenopausal women, achieved through its effects on metabolic risk factors for coronary heart disease (CHD) and on arterial function. Observational studies have consistently shown an association between postmenopausal HRT use and a reduced incidence of CHD. However, the largest randomised trial initially reported no overall benefit on CHD risk. Subsequent analyses ...

Short communications

Breast cancer prevention trumps cureSubscription

By ,

Breast cancer is the most prevalent female cancer and is estimated to increase by 50% by 2030 compared to the incidence in 2011. The decision by the National Institute for Health and Care Excellence (NICE), the UK health technology appraiser, to recommend the use of preventive medicines, which are known to decrease the risk of developing breast cancer, is a welcome advance in public health.

We need safe and better labelled vitamin D products on the marketSubscription

By

Recommended vitamin D intakes for all of us living in the UK have changed following the publication of a report from the Scientific Advisory Committee on Nutrition (SACN) on 22 July 2016. New guidelines were required because of the persisting problem relating to vitamin D deficiency: ...

Parkinson’s disease-specific medicines use reviewSubscription

By

Members of Royal Pharmaceutical Society’s London North West Local Practice Forum (LNW LPF) are working with charity Parkinson’s UK to develop a new service for patients with Parkinson’s disease (PD). The overall aim is to develop a PD-specific medicines use review by designing and trialling it in an initial and follow-up trial.

How to spot signs of postnatal depression in the pharmacySubscription

By

In light of singer Adele’s recent admission in an interview that she has suffered from postnatal depression (PND), I would like to alert readers to how they can spot the signs and help those who might be affected in their day-to-day work in the pharmacy.

Research briefing

GP takes blood pressure of patient

Ambulatory blood pressure higher than clinic BP, study showsSubscription

3 JAN 2017

Researchers say 24-hour ambulatory BP monitoring could benefit people with prehypertension following trial of 888 people. 

Older patient using a frame

Pharmacist review boosts detection of inappropriate prescribingSubscription

3 JAN 2017

Inclusion of a pharmacist in the multidisciplinary team could detect more cases of potentially inappropriate prescribing, study results suggest.

Feet of newborn baby

Vitamin D levels at birth linked to MS risk in later lifeSubscription

30 DEC 2016

Researchers found an inverse relationship between vitamin D levels in dried blood spots up to seven days after birth and the risk of developing MS in later life. 

MRI showing intracerebral haemorrhage

Proton pump inhibitors may increase risk of first stroke Subscription

29 DEC 2016

Data from 244,679 patients that had undergone endoscopy show that stroke incidence was 19% higher in patients who filed a prescription for a PPI compared with those with no PPI exposure

Clinical Pharmacist

CP January 2017, Vol 9, No 1

Cover Story:

Sepsis: an update on identification and management

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Clinical Pharmacist

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Clinical Pharmacist is a monthly, peer-reviewed journal that provides authoritative resources on the clinical management of disease in relation to medicines and up-to-date information about advances in pharmacy and drug development. Clinical Pharmacist publishes Review articles, Perspectives, evidence-based CPD articles and Research articles on topics from drug discovery to clinical pharmacology and pharmacy.

The international audience of Pharmaceutical Journal Publications consists of pharmacists, pharmaceutical scientists and healthcare professionals. The journal is available to 44,000 members of the Royal Pharmaceutical Society, as well as non-member individual subscribers and subscribing institutions.