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Illustration showing the path of pain and its inhibition at the level of the neurons of the spinal cord

Treatments for neuropathic painSubscription

Clinical Pharmacist, Vol 9, No 12By ,

Abstract: Neuropathic pain (NP) is a common condition characterised by subjective negative and positive symptoms that range from numbness to debilitating pain. NP can have a significant negative impact on a patient’s quality of life. Pharmacotherapy is typically the first step in treating NP. Guidelines and consensus statements from various organisations around the world appear to be consistent with the classes of medications recommended for both general and specific types of NP, which ...

Abstract illustration of pain - naked man standing against red background

Pharmacological treatment options for fibromyalgiaSubscription

7 NOV 2017By , ,

Fibromyalgia is a high-impact and prevalent condition. Its clinical features include widespread pain and tenderness — often associated with high levels of poor-quality sleep, fatigue and cognitive dysfunction. The mechanism leading to fibromyalgia development is associated with a change in the sensitivity of the pain-related nervous system, as well as other sensory systems. In turn, emotional distress plays a facilitatory role in this process. Non-pharmacological management focuses ...

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Molecular model of C-reactive protein

Evaluating a point-of-care C-reactive protein test to support antibiotic prescribing decisions in a general practiceSubscription

By , , ,

C-reactive protein (CRP) is a marker of infection and inflammation. It is high in bacterial infections but very low or close to zero in viral infections. The National Institute for Health and Care Excellence (NICE), England and Wales’s health technology assessment body, has issued guidance on pneumonia in adults; it recommends point-of-care (POC) CRP analysers when clinical assessment is inconclusive. If the CRP level is less than 20mg/L, no antibiotics ...

Oral anticoagulant therapy and INR blood test monitor

Assessing the impact of a targeted pharmacist-led anticoagulant review clinicSubscription

By , , ,

Local guidance, supported by the 2014 National Institute for Health and Care Excellence (NICE) guideline CG180 for atrial fibrillation (AF), recommends that patients receiving inadequate anticoagulation with a vitamin K antagonist (VKA), including time in therapeutic range (TTR) of <65%, should be reassessed. These patients were identified by the anticoagulation monitoring service (AMS) and highlighted to GPs for review. However, up to 59.3% of patients received ...

Close-up of a person taking a dry-blood spot test

Integrating community pharmacy testing for hepatitis C with specialist careSubscription

By , Pembe Hassan-Hicks, Kevin Noble, Leonie Grellier, Julie Parkes, Salim I Khakoo

Many patients with hepatitis C virus (HCV) infection lie undiagnosed and a significant proportion of patients that have been identified are disengaged from specialist services. The Isle of Wight (IOW) typifies this issue, with an estimated 200 undiagnosed patients with HCV infection and a small number of known cases engaged with specialist services. Aim: To reduce the burden of undiagnosed HCV on the IOW and link new diagnoses directly ...

Elderly man consults with a carer about his medicines

Pharmacy at home: service for frail older patients demonstrates medicines risk reduction and admission avoidanceSubscription

By , , ,

The Exeter Cluster Pharmacy (ECP) team is part of an integrated community health and social care service, providing domiciliary medicines optimisation to around 145,000 people. The service undertakes clinical medication reviews for frail older people at home, assessing their risk of medicine-related harm in order to reduce these risks and potentially prevent hospital admissions. Objective: An evaluation was completed in 2014 to assess the level of service the pharmacy ...

How useful are medicines helplines for patients discharged from hospital?Subscription

By , , Szn-Fang Li

This paper suggests that patient helplines support medicines optimisation by ensuring patients have easy access to pharmacy experts to discuss concerns about their medicines and improve the quality of their pharmaceutical care.

The package user test: a method for improving medicines packaging Subscription

By ,

This paper describes a new performance-based package user test that has the potential to improve drug package design and therefore reduce drug selection errors.

We are all part virus — the role of human endogenous retrovirusesSubscription

By ,

Viruses lurk in our genome and science is only now starting to understand the important role that they might play in health and disease. Kalliopi Dodou and Paul Whiteley explain.

Integrated examinations: supporting students with team-based learningSubscription

By , , ,

Jason Hall and colleagues explain how Manchester Pharmacy School is applying team-based learning to the MPharm course to integrate science and practice modules.

A review of Controlled Drug incidents reported to the NRLS over seven yearsSubscription

To describe the number and types of patient safety incidents involving Controlled Drugs reported to the National Reporting and Learning System (NRLS) and the role of Accountable Officers for CDs (AOs) in incident reporting and learning.

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