Statin dose timing

28 October 2014: The Daily Mail reported that statins “work best if they are taken before bedtime”, as individual genes “become more or less active at certain times of the day”. Speaking about simvastatin, Royal Pharmaceutical Society spokeswoman Heidi Wright said: “Simvastatin is best taken at bedtime as your liver makes most of your cholesterol at night. Low-dose aspirin works by making your blood less sticky. There is research that says more heart attacks occur in the morning, so reducing this stickiness by the morning could help prevent heart attacks.”

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Citation
The Pharmaceutical Journal, PJ, 15 November 2014, Vol 293, No 7836;293(7836):DOI:10.1211/PJ.2014.20067122

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