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Antibiotic resistance: A fragile defence

Last defence dam in antimicrobial resistance

Around 25,000 people die in the European Union each year from infections resistant to antibiotics. Third-generation cephalosporins are often useless against common bacteria like Escherichia coli, and fluoroquinolones are no longer the treatment of choice for gonorrhoea because resistance has become widespread. Here, you can find news stories and articles about the issue.

Dilip Nathwani (left) current president British Society of Antimicrobial Chemotherapy and Philip Howard, president-elect

British Society of Antimicrobial Chemotherapy appoints first pharmacist president

The British Society of Antimicrobial Chemotherapy (BSAC) has, for the first time in its 45-year history, appointed a pharmacist to be its president.

Petri dish with clostridium difficile culture

Recent C. difficile reduction in England mostly results from antibiotic stewardshipSubscription

Restricting the prescribing of fluoroquinolone seems to explain the reduced rates of C. difficile infections in England over the past decade, national study shows.

Salmonella bacteria, micrograph

WHO lists bacteria that need to be targeted for antibiotic development

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The World Health Organization has drawn up a list of families of bacteria that pose the greatest risk to human health and which should be targeted by drug companies when developing new antibiotics.

Professor Colin Garner of Antibiotic Research UK

Antibiotic policies reduce unnecessary use in hospitals and cut lengths of stays

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Antibiotic stewardship interventions are more effective if they contain enabling components, such as goal setting, feedback and action planning, say the authors of an updated Cochrane review.

More on antimicrobial resistance

Micrograph of Clostridium difficile bacteria

Clostridium difficile: diagnosis and treatment update

By , Christopher Eades, Luke SP Moore,

There are around 12,000 cases of Clostridium difficile infection (CDI) each year in the UK and during 1999 to 2007, deaths from CDI peaked at around 4,000 per year. This article summarises diagnosis and management, as well as the current therapeutic options for CDI, including faecal microbiota transplant.

Collage showing MRSA, research and antibiotics

New approaches to overcoming antimicrobial resistanceSubscription

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As antibiotic resistance continues to threaten the treatment of various infections, researchers are looking for new ways to supplement and in some cases replace failing antimicrobial drugs.

Illustration antibiotic destroying bacteria

Principles of initiating antimicrobial therapy and empiric prescribingSubscription

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Healthcare professionals should be aware of the principles of antimicrobial treatment and the need to reduce inappropriate prescribing to retain the effectiveness of drugs currently available.

More on antimicrobial resistance

Illustration showing alarm due to rise of antimicrobial resistant bacteria from biocides and heavy metals

How chemicals and heavy metals contribute to antimicrobial resistanceSubscription

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Evidence is emerging that biocides and heavy metals all contribute to the growing problem of antimicrobial resistance.

Balancing action on antimicrobial resistance with animal welfareSubscription

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As almost everyone in the business of caring for the health of humans and animals is acutely aware, on our current trajectory, it is estimated that antimicrobial resistance (AMR) will cause 10 million deaths annually by 2050, with many arising from simple infections following routine operations. This is why the UK government has placed antimicrobial resistance at the top of its risk register alongside terrorism and pandemic influenza.

From left (top), Tedros Adhanom Ghebreyesus, Flavia Bustreo, Philippe Douste-Blazy, (bottom) David Nabarro, Sania Nishtar and Miklós Szócska

Q&A: WHO director-general candidates’ views on global healthSubscription

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Six candidates in the race to be director-general of the World Health Organization outline their priorities and vision for global health.

Tim Evans is the senior director of health, nutrition and population at the World Bank Group

Q&A: World Bank warns that inaction on antimicrobial resistance could increase healthcare costs in developing countriesSubscription

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Tim Evans from the World Bank Group talks about new research that shows how inaction on antimicrobial resistance could wipe out decades of healthcare gains and dramatically increase healthcare costs in developing countries.

More on antimicrobial resistance

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